Behçet's disease: the first Mongolian case in literature showing HLA B51, MICA gene type 5/6
Behçet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-...
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| Veröffentlicht in: | Yonsei medical journal 2003-10, Vol.44 (5), p.935-938 |
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| container_title | Yonsei medical journal |
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| creator | Chung, Yae Lee Bang, Dong Sik Lee, Eun-So Lee, Sung Nack Mok, Jee Won Park, Kyung Sook |
| description | Behçet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-along the Silk Road-, and in Japan, China, and Korea. Recently, we treated a Mongolian patient who had complete-type Behçet's disease. As far as we know, this case is the first report of a Mongolian with Behçet's disease in the English literature. HLA typing in this patient revealed A2, A24;B51, B35; Cw4, Cw7; DR9, DR11. Study of the MICA genetype showed *5, *6 positive. Our data provided adequate evidence, from an epidemiological aspect, to support the belief that Behçet's disease is most prevalent along the old Silk Road. |
| doi_str_mv | 10.3349/ymj.2003.44.5.935 |
| format | Article |
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The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-along the Silk Road-, and in Japan, China, and Korea. Recently, we treated a Mongolian patient who had complete-type Behçet's disease. As far as we know, this case is the first report of a Mongolian with Behçet's disease in the English literature. HLA typing in this patient revealed A2, A24;B51, B35; Cw4, Cw7; DR9, DR11. Study of the MICA genetype showed *5, *6 positive. Our data provided adequate evidence, from an epidemiological aspect, to support the belief that Behçet's disease is most prevalent along the old Silk Road.</description><subject>Adult</subject><subject>Alleles</subject><subject>Behcet Syndrome - genetics</subject><subject>Behcet Syndrome - immunology</subject><subject>Genotype</subject><subject>Histocompatibility Antigens Class I - genetics</subject><subject>HLA-B Antigens - genetics</subject><subject>HLA-B51 Antigen</subject><subject>Humans</subject><subject>Male</subject><issn>0513-5796</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkLtOwzAYhT2AaCk8AAvyBAtJfU_N1lZAkVqxwIgsJ_nTpsql2IlQn4gH4cVw1UpMZzjfOcOH0A0lMedCj_f1NmaE8FiIWMaayzM0JJLySCZaDdCl91tCWEIJu0ADKuREUKqG6HMGm98f6O49zksP1sMj7jaAi9L5Dq_aZt1WpW1wFhpcNrgqO3C26x1gv2m_y2aNF8spnkn6gFev8yleQwO42-8Ay7G6QueFrTxcn3KEPp6f3ueLaPn2EuBllDEpZcSUFqmaMJ2ogkqtqKYChFJW0SxPtc3TjEyEFURkUotiktI0wAQCbC0vMj5Cd8ffnWu_evCdqUufQVXZBtrem4RyxhLFAkiPYOZa7x0UZufK2rq9ocQcPJrg0Rw8GiGMNMFj2Nyezvu0hvx_cZLI_wA0mm7Q</recordid><startdate>20031030</startdate><enddate>20031030</enddate><creator>Chung, Yae Lee</creator><creator>Bang, Dong Sik</creator><creator>Lee, Eun-So</creator><creator>Lee, Sung Nack</creator><creator>Mok, Jee Won</creator><creator>Park, Kyung Sook</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0232-7704</orcidid></search><sort><creationdate>20031030</creationdate><title>Behçet's disease: the first Mongolian case in literature showing HLA B51, MICA gene type 5/6</title><author>Chung, Yae Lee ; Bang, Dong Sik ; Lee, Eun-So ; Lee, Sung Nack ; Mok, Jee Won ; Park, Kyung Sook</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2555-2694b682976f15961914e466a61cdb9adbc084a404c594f8b1b8290ef15aa3fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Alleles</topic><topic>Behcet Syndrome - genetics</topic><topic>Behcet Syndrome - immunology</topic><topic>Genotype</topic><topic>Histocompatibility Antigens Class I - genetics</topic><topic>HLA-B Antigens - genetics</topic><topic>HLA-B51 Antigen</topic><topic>Humans</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chung, Yae Lee</creatorcontrib><creatorcontrib>Bang, Dong Sik</creatorcontrib><creatorcontrib>Lee, Eun-So</creatorcontrib><creatorcontrib>Lee, Sung Nack</creatorcontrib><creatorcontrib>Mok, Jee Won</creatorcontrib><creatorcontrib>Park, Kyung Sook</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Yonsei medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chung, Yae Lee</au><au>Bang, Dong Sik</au><au>Lee, Eun-So</au><au>Lee, Sung Nack</au><au>Mok, Jee Won</au><au>Park, Kyung Sook</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Behçet's disease: the first Mongolian case in literature showing HLA B51, MICA gene type 5/6</atitle><jtitle>Yonsei medical journal</jtitle><addtitle>Yonsei Med J</addtitle><date>2003-10-30</date><risdate>2003</risdate><volume>44</volume><issue>5</issue><spage>935</spage><epage>938</epage><pages>935-938</pages><issn>0513-5796</issn><abstract>Behçet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-along the Silk Road-, and in Japan, China, and Korea. Recently, we treated a Mongolian patient who had complete-type Behçet's disease. As far as we know, this case is the first report of a Mongolian with Behçet's disease in the English literature. HLA typing in this patient revealed A2, A24;B51, B35; Cw4, Cw7; DR9, DR11. Study of the MICA genetype showed *5, *6 positive. Our data provided adequate evidence, from an epidemiological aspect, to support the belief that Behçet's disease is most prevalent along the old Silk Road.</abstract><cop>Korea (South)</cop><pmid>14584116</pmid><doi>10.3349/ymj.2003.44.5.935</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-0232-7704</orcidid><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | MEDLINE; KoreaMed Open Access; EZB Electronic Journals Library |
| subjects | Adult Alleles Behcet Syndrome - genetics Behcet Syndrome - immunology Genotype Histocompatibility Antigens Class I - genetics HLA-B Antigens - genetics HLA-B51 Antigen Humans Male |
| title | Behçet's disease: the first Mongolian case in literature showing HLA B51, MICA gene type 5/6 |
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