Modulation of the pharmacokinetics of macromolecular contrast material by avidin chase: MRI, optical, and inductively coupled plasma mass spectrometry tracking of triply labeled albumin

The goal of this work was to develop an MRI method for mapping the clearance of interstitial macromolecular plasma proteins after their extravasation from permeable blood vessels. To that end, a well‐defined window of exposure to elevated blood levels was generated by inducing rapid clearance of mac...

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Veröffentlicht in:Magnetic resonance in medicine 2003-11, Vol.50 (5), p.904-914
Hauptverfasser: Dafni, Hagit, Gilead, Assaf, Nevo, Nava, Eilam, Raya, Harmelin, Alon, Neeman, Michal
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Sprache:eng
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