Donor cell expansion is delayed following nonablative in utero transplantation to treat murine mucopolysaccharidosis type VII

To block development of progressive childhood diseases, in utero transplantation (IUTx) requires immediate and significant donor peripheral blood (PB) cell amplification. To date, negligible and nontherapeutic donor PB cell levels have been observed postnatally, except in patients with immunodeficie...

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Veröffentlicht in:	Experimental hematology 2003-11, Vol.31 (11), p.1112-1118
Hauptverfasser:	Barker, Jane E, Schuldt, Adam J.T, Lessard, Mark L, Jude, Craig D, Vogler, Carole A, Soper, Brian W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Count Female Fetal Diseases - therapy Glucuronidase - analysis Male Mice Mice, Inbred BALB C Mice, Inbred C57BL Mucopolysaccharidosis VII - therapy Stem Cell Transplantation - methods Time Factors
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