Alterations in the phenotype of CMV-specific and total CD8 + T-cell populations in Wegener’s granulomatosis

Wegener’s granulomatosis (WG) is an autoimmune disease of as yet unknown etiology. To date it has remained obscure what causes WG or determines disease progression. Case reports suggest that viral infections such as cytomegalovirus (CMV) reactivation may contribute to disease flares. In this study w...

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Veröffentlicht in:	Cellular immunology 2003-07, Vol.224 (1), p.1-7
Hauptverfasser:	Lamprecht, Peter, Vargas Cuero, Ana L., Muller, Antje, Csernok, Elena, Voswinkel, Jan, Maass, Matthias, Solbach, Werner, Gross, Wolfgang L., Klenerman, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase - immunology ADP-ribosyl Cyclase 1 Antigens, CD - immunology Antigens, Differentiation, T-Lymphocyte - immunology CD28 Antigens - immunology CD57 Antigens - immunology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - virology Cell Differentiation - drug effects Cell Differentiation - immunology Cytomegalovirus - immunology Cytomegalovirus - pathogenicity Cytomegalovirus Infections - complications Down-Regulation - immunology Female Granulomatosis with Polyangiitis - blood Granulomatosis with Polyangiitis - immunology Granulomatosis with Polyangiitis - virology HLA-DR Antigens - immunology Humans Immunosuppressive Agents - pharmacology L-Selectin - immunology Lectins, C-Type Male Membrane Glycoproteins Phenotype Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology Up-Regulation - immunology
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