Metabolic engineering for the microbial production of 1,3-propanediol
Improvements in the biological production of 1,3-propanediol, a key component of an emerging polymer business, have been realized. Utilizing genes from natural strains that produce 1,3-propanediol from glycerol, metabolic engineering has enabled the development of a recombinant strain that utilizes...
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| Veröffentlicht in: | Current opinion in biotechnology 2003-10, Vol.14 (5), p.454-459 |
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| container_title | Current opinion in biotechnology |
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| creator | Nakamura, Charles E Whited, Gregory M |
| description | Improvements in the biological production of 1,3-propanediol, a key component of an emerging polymer business, have been realized. Utilizing genes from natural strains that produce 1,3-propanediol from glycerol, metabolic engineering has enabled the development of a recombinant strain that utilizes the lower cost feedstock
d-glucose. This accomplishment bodes well for future metabolic engineering efforts and, ultimately, for increased societal benefit obtained through the production of chemicals from renewable resources. |
| doi_str_mv | 10.1016/j.copbio.2003.08.005 |
| format | Article |
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| ispartof | Current opinion in biotechnology, 2003-10, Vol.14 (5), p.454-459 |
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| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | 1,3-propanediol Bacteria - genetics Bacteria - metabolism Biological Transport Catalysis Cobamides - metabolism Fermentation glucose Glucose - metabolism glycerol Industrial Microbiology Propylene Glycols - chemical synthesis Propylene Glycols - metabolism Protein Engineering - methods |
| title | Metabolic engineering for the microbial production of 1,3-propanediol |
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