Age Increases Expression and Receptor-Mediated Activation of Gαi in Human Atria

Recently, we demonstrated that β2AR and several other Gαs-coupled receptors in human atria also couple to Gαi, a G protein that inhibits adenylyl cyclase (AC). The present study was undertaken to determine whether age increases expression of Gαi in human atrium, and more specifically whether it resu...

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