The I1307K Adenomatous Polyposis Coli Gene Variant Does Not Contribute in the Assessment of the Risk for Colorectal Cancer in Ashkenazi Jews

Ashkenazi Jews with the I1307K adenomatous polyposis coli gene variant were suggested to confer a higher risk for colorectal cancer (CRC). We assessed the clinical importance of this polymorphism in Israeli Jews at average and elevated risk for CRC. Among 1370 consecutive subjects that were examined...

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