A case of a diffuse large B-cell lymphoma of plasmablastic type associated with the t(2;5)(p23;q35) chromosome translocation

Anaplastic large cell lymphomas are associated with the t(2;5)(p23;q35) chromosome translocation in 40% to 60% of cases, leading to a new chimeric gene NPM-ALK. NPM-ALK positive lymphomas are generally reported to be of either T cell or null phenotype. In this report, we describe a diffuse large B-c...

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Veröffentlicht in:	The American journal of surgical pathology 2003-11, Vol.27 (11), p.1473-1476
Hauptverfasser:	ADAM, Patrick, KATZENBERGER, Tiemo, SEEBERGER, Harald, GATTENLÖHNER, Stefan, WOLF, Juergen, STEINLEIN, Claus, SCHMID, Michael, MÜLLER-HERMELINK, Hans-Konrad, OTT, German
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anaplastic Lymphoma Kinase Biological and medical sciences Chromosome aberrations Chromosomes, Human, Pair 2 Chromosomes, Human, Pair 5 DNA, Neoplasm - analysis Hematologic and hematopoietic diseases Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - genetics Lymphoma, B-Cell - metabolism Lymphoma, B-Cell - pathology Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - metabolism Lymphoma, Large B-Cell, Diffuse - pathology Male Medical genetics Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - metabolism Receptor Protein-Tyrosine Kinases Reverse Transcriptase Polymerase Chain Reaction Spectral Karyotyping Translocation, Genetic
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