Survival, morbidity, and quality of life after discharge from intensive care
OBJECTIVETo assess survival, morbidity (physical and psychological), quality of life (QOL), and employment status of intensive care survivors up to 12 months after discharge from the intensive care unit (ICU). DESIGNProspective study. SETTINGUniversity hospital adult ICU. PATIENTSBetween August 1, 1...
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| Veröffentlicht in: | Critical care medicine 2000-07, Vol.28 (7), p.2293-2299 |
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| creator | Eddleston, Jane M White, Pauline Guthrie, Else |
| description | OBJECTIVETo assess survival, morbidity (physical and psychological), quality of life (QOL), and employment status of intensive care survivors up to 12 months after discharge from the intensive care unit (ICU).
DESIGNProspective study.
SETTINGUniversity hospital adult ICU.
PATIENTSBetween August 1, 1995, and July 31, 1996, 370 patients were admitted. Of these patients, 29% died in the ICU. Three months after discharge from the ICU, 227 patients were alive, and 143 agreed to participate. Cumulative mortality was calculated using the original complete cohort.
MEASUREMENTS AND MAIN RESULTSDemographic data, severity of acute illness (Acute Physiology and Chronic Health Evaluation [APACHE] II), admitting specialty, primary diagnosis, and length of stay were recorded. Physical and ICU-related psychological morbidity (Hospital Anxiety and Depression scale score) were recorded. Health-related QOL was assessed using the Short-Form 36. All the questionnaires were completed in the clinic at 3 months. Assessment of physical morbidity and employment status at 6 and 12 months were conducted by telephone. The cumulative mortality was 39% at 3 months, 41% at 6 months, and 43% at 12 months. Deaths after 3 months occurred in the group who refused follow-up. The median age for the follow-up group was 51 yrs; the gender split was 68 women and 75 men; the mean admission APACHE II score was 18.79 (sd 6.15); and the median length of ICU stay was 3.8 days.At 3 months, ∼80% of all patients interviewed were satisfied with their QOL. Older men (>65 yrs) and younger women ( |
| doi_str_mv | 10.1097/00003246-200007000-00018 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71301727</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71301727</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4518-b3d3465e266067c7b39071cb5cc1cd9ddf044c4685fb208bc52758937d8fcf183</originalsourceid><addsrcrecordid>eNp1kUtPxCAQgInR6Lr6FwwH48kqFCjt0Wx8JZt4UM-E8nBR2rrQrtl_L2vXx0WSCUzyzQx8AAAxusCo4pcoLZLTIss3J54iS4HLHTDBjKQkr8gumCBUoYzQihyAwxhfE0EZJ_vgIDXJMWNsAuaPQ1i5lfTnsOlC7bTr1-dQthouB-lTAjsLvbMGStubALWLaiHDi4E2dA10bW_a6FYGKhnMEdiz0kdzvN2n4Pnm-ml2l80fbu9nV_NMUYbLrCaa0IKZvChQwRWvSYU4VjVTCitdaW0RpYoWJbN1jspasZyzsiJcl1ZZXJIpOBv7voduOZjYiyZdy3gvW9MNUXBMEOY5T2A5gip0MQZjxXtwjQxrgZHYmBTfJsWPSfFlMpWebGcMdWP0n8JRXQJOt4CMSnobZKtc_OXSUxGiCaMj9tH5JDC--eHDBLEw0vcL8d9Hkk8I-ImV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71301727</pqid></control><display><type>article</type><title>Survival, morbidity, and quality of life after discharge from intensive care</title><source>MEDLINE</source><source>Journals@Ovid Ovid Autoload</source><creator>Eddleston, Jane M ; White, Pauline ; Guthrie, Else</creator><creatorcontrib>Eddleston, Jane M ; White, Pauline ; Guthrie, Else</creatorcontrib><description>OBJECTIVETo assess survival, morbidity (physical and psychological), quality of life (QOL), and employment status of intensive care survivors up to 12 months after discharge from the intensive care unit (ICU).
DESIGNProspective study.
SETTINGUniversity hospital adult ICU.
PATIENTSBetween August 1, 1995, and July 31, 1996, 370 patients were admitted. Of these patients, 29% died in the ICU. Three months after discharge from the ICU, 227 patients were alive, and 143 agreed to participate. Cumulative mortality was calculated using the original complete cohort.
MEASUREMENTS AND MAIN RESULTSDemographic data, severity of acute illness (Acute Physiology and Chronic Health Evaluation [APACHE] II), admitting specialty, primary diagnosis, and length of stay were recorded. Physical and ICU-related psychological morbidity (Hospital Anxiety and Depression scale score) were recorded. Health-related QOL was assessed using the Short-Form 36. All the questionnaires were completed in the clinic at 3 months. Assessment of physical morbidity and employment status at 6 and 12 months were conducted by telephone. The cumulative mortality was 39% at 3 months, 41% at 6 months, and 43% at 12 months. Deaths after 3 months occurred in the group who refused follow-up. The median age for the follow-up group was 51 yrs; the gender split was 68 women and 75 men; the mean admission APACHE II score was 18.79 (sd 6.15); and the median length of ICU stay was 3.8 days.At 3 months, ∼80% of all patients interviewed were satisfied with their QOL. Older men (>65 yrs) and younger women (<65 yrs) demonstrated significantly better health with respect to some subdomains of the Short-Form 36 compared with their counterparts. The prevalence of psychological distress (Hospital Anxiety and Depression scale score, ≥8) was low11.9% had heightened anxiety, and 9.8% were depressed. There were high levels of fatigue, poor concentration, and sleep disturbance; the latter was more marked in women (p = .022). Improvement in all three symptoms occurred during the next 9 months. Significantly more women reported loss of hair (p < .0001). Men were slower to return to employment; 75% of women had returned by 6 months compared with only 65% of men at 1 yr.
CONCLUSIONAssessment of outcome after ICU stay must include QOL measurements. Three months after discharge, there is a low incidence of ICU-related psychological or psychiatric illness and the majority of patients are satisfied. Differences in the incidence and nature of morbidity exist between the genders.</description><identifier>ISSN: 0090-3493</identifier><identifier>EISSN: 1530-0293</identifier><identifier>DOI: 10.1097/00003246-200007000-00018</identifier><identifier>PMID: 10921555</identifier><identifier>CODEN: CCMDC7</identifier><language>eng</language><publisher>Hagerstown, MD: Copyright by by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc</publisher><subject>Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; APACHE ; Biological and medical sciences ; Employment ; Female ; Health Status ; Health Surveys ; Hospital Mortality ; Humans ; Intensive care medicine ; Intensive Care Units ; Length of Stay ; Male ; Medical sciences ; Mental Health ; Middle Aged ; Miscellaneous ; Morbidity ; Patient Discharge ; Patient Satisfaction ; Prospective Studies ; Quality of Life ; Sex Distribution ; Surveys and Questionnaires ; Survival Rate</subject><ispartof>Critical care medicine, 2000-07, Vol.28 (7), p.2293-2299</ispartof><rights>Copyright © by 2000 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4518-b3d3465e266067c7b39071cb5cc1cd9ddf044c4685fb208bc52758937d8fcf183</citedby><cites>FETCH-LOGICAL-c4518-b3d3465e266067c7b39071cb5cc1cd9ddf044c4685fb208bc52758937d8fcf183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1451004$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10921555$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eddleston, Jane M</creatorcontrib><creatorcontrib>White, Pauline</creatorcontrib><creatorcontrib>Guthrie, Else</creatorcontrib><title>Survival, morbidity, and quality of life after discharge from intensive care</title><title>Critical care medicine</title><addtitle>Crit Care Med</addtitle><description>OBJECTIVETo assess survival, morbidity (physical and psychological), quality of life (QOL), and employment status of intensive care survivors up to 12 months after discharge from the intensive care unit (ICU).
DESIGNProspective study.
SETTINGUniversity hospital adult ICU.
PATIENTSBetween August 1, 1995, and July 31, 1996, 370 patients were admitted. Of these patients, 29% died in the ICU. Three months after discharge from the ICU, 227 patients were alive, and 143 agreed to participate. Cumulative mortality was calculated using the original complete cohort.
MEASUREMENTS AND MAIN RESULTSDemographic data, severity of acute illness (Acute Physiology and Chronic Health Evaluation [APACHE] II), admitting specialty, primary diagnosis, and length of stay were recorded. Physical and ICU-related psychological morbidity (Hospital Anxiety and Depression scale score) were recorded. Health-related QOL was assessed using the Short-Form 36. All the questionnaires were completed in the clinic at 3 months. Assessment of physical morbidity and employment status at 6 and 12 months were conducted by telephone. The cumulative mortality was 39% at 3 months, 41% at 6 months, and 43% at 12 months. Deaths after 3 months occurred in the group who refused follow-up. The median age for the follow-up group was 51 yrs; the gender split was 68 women and 75 men; the mean admission APACHE II score was 18.79 (sd 6.15); and the median length of ICU stay was 3.8 days.At 3 months, ∼80% of all patients interviewed were satisfied with their QOL. Older men (>65 yrs) and younger women (<65 yrs) demonstrated significantly better health with respect to some subdomains of the Short-Form 36 compared with their counterparts. The prevalence of psychological distress (Hospital Anxiety and Depression scale score, ≥8) was low11.9% had heightened anxiety, and 9.8% were depressed. There were high levels of fatigue, poor concentration, and sleep disturbance; the latter was more marked in women (p = .022). Improvement in all three symptoms occurred during the next 9 months. Significantly more women reported loss of hair (p < .0001). Men were slower to return to employment; 75% of women had returned by 6 months compared with only 65% of men at 1 yr.
CONCLUSIONAssessment of outcome after ICU stay must include QOL measurements. Three months after discharge, there is a low incidence of ICU-related psychological or psychiatric illness and the majority of patients are satisfied. Differences in the incidence and nature of morbidity exist between the genders.</description><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>APACHE</subject><subject>Biological and medical sciences</subject><subject>Employment</subject><subject>Female</subject><subject>Health Status</subject><subject>Health Surveys</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Intensive Care Units</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental Health</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Morbidity</subject><subject>Patient Discharge</subject><subject>Patient Satisfaction</subject><subject>Prospective Studies</subject><subject>Quality of Life</subject><subject>Sex Distribution</subject><subject>Surveys and Questionnaires</subject><subject>Survival Rate</subject><issn>0090-3493</issn><issn>1530-0293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUtPxCAQgInR6Lr6FwwH48kqFCjt0Wx8JZt4UM-E8nBR2rrQrtl_L2vXx0WSCUzyzQx8AAAxusCo4pcoLZLTIss3J54iS4HLHTDBjKQkr8gumCBUoYzQihyAwxhfE0EZJ_vgIDXJMWNsAuaPQ1i5lfTnsOlC7bTr1-dQthouB-lTAjsLvbMGStubALWLaiHDi4E2dA10bW_a6FYGKhnMEdiz0kdzvN2n4Pnm-ml2l80fbu9nV_NMUYbLrCaa0IKZvChQwRWvSYU4VjVTCitdaW0RpYoWJbN1jspasZyzsiJcl1ZZXJIpOBv7voduOZjYiyZdy3gvW9MNUXBMEOY5T2A5gip0MQZjxXtwjQxrgZHYmBTfJsWPSfFlMpWebGcMdWP0n8JRXQJOt4CMSnobZKtc_OXSUxGiCaMj9tH5JDC--eHDBLEw0vcL8d9Hkk8I-ImV</recordid><startdate>200007</startdate><enddate>200007</enddate><creator>Eddleston, Jane M</creator><creator>White, Pauline</creator><creator>Guthrie, Else</creator><general>Copyright by by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200007</creationdate><title>Survival, morbidity, and quality of life after discharge from intensive care</title><author>Eddleston, Jane M ; White, Pauline ; Guthrie, Else</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4518-b3d3465e266067c7b39071cb5cc1cd9ddf044c4685fb208bc52758937d8fcf183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>APACHE</topic><topic>Biological and medical sciences</topic><topic>Employment</topic><topic>Female</topic><topic>Health Status</topic><topic>Health Surveys</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Intensive Care Units</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental Health</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Morbidity</topic><topic>Patient Discharge</topic><topic>Patient Satisfaction</topic><topic>Prospective Studies</topic><topic>Quality of Life</topic><topic>Sex Distribution</topic><topic>Surveys and Questionnaires</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eddleston, Jane M</creatorcontrib><creatorcontrib>White, Pauline</creatorcontrib><creatorcontrib>Guthrie, Else</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eddleston, Jane M</au><au>White, Pauline</au><au>Guthrie, Else</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survival, morbidity, and quality of life after discharge from intensive care</atitle><jtitle>Critical care medicine</jtitle><addtitle>Crit Care Med</addtitle><date>2000-07</date><risdate>2000</risdate><volume>28</volume><issue>7</issue><spage>2293</spage><epage>2299</epage><pages>2293-2299</pages><issn>0090-3493</issn><eissn>1530-0293</eissn><coden>CCMDC7</coden><abstract>OBJECTIVETo assess survival, morbidity (physical and psychological), quality of life (QOL), and employment status of intensive care survivors up to 12 months after discharge from the intensive care unit (ICU).
DESIGNProspective study.
SETTINGUniversity hospital adult ICU.
PATIENTSBetween August 1, 1995, and July 31, 1996, 370 patients were admitted. Of these patients, 29% died in the ICU. Three months after discharge from the ICU, 227 patients were alive, and 143 agreed to participate. Cumulative mortality was calculated using the original complete cohort.
MEASUREMENTS AND MAIN RESULTSDemographic data, severity of acute illness (Acute Physiology and Chronic Health Evaluation [APACHE] II), admitting specialty, primary diagnosis, and length of stay were recorded. Physical and ICU-related psychological morbidity (Hospital Anxiety and Depression scale score) were recorded. Health-related QOL was assessed using the Short-Form 36. All the questionnaires were completed in the clinic at 3 months. Assessment of physical morbidity and employment status at 6 and 12 months were conducted by telephone. The cumulative mortality was 39% at 3 months, 41% at 6 months, and 43% at 12 months. Deaths after 3 months occurred in the group who refused follow-up. The median age for the follow-up group was 51 yrs; the gender split was 68 women and 75 men; the mean admission APACHE II score was 18.79 (sd 6.15); and the median length of ICU stay was 3.8 days.At 3 months, ∼80% of all patients interviewed were satisfied with their QOL. Older men (>65 yrs) and younger women (<65 yrs) demonstrated significantly better health with respect to some subdomains of the Short-Form 36 compared with their counterparts. The prevalence of psychological distress (Hospital Anxiety and Depression scale score, ≥8) was low11.9% had heightened anxiety, and 9.8% were depressed. There were high levels of fatigue, poor concentration, and sleep disturbance; the latter was more marked in women (p = .022). Improvement in all three symptoms occurred during the next 9 months. Significantly more women reported loss of hair (p < .0001). Men were slower to return to employment; 75% of women had returned by 6 months compared with only 65% of men at 1 yr.
CONCLUSIONAssessment of outcome after ICU stay must include QOL measurements. Three months after discharge, there is a low incidence of ICU-related psychological or psychiatric illness and the majority of patients are satisfied. Differences in the incidence and nature of morbidity exist between the genders.</abstract><cop>Hagerstown, MD</cop><pub>Copyright by by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc</pub><pmid>10921555</pmid><doi>10.1097/00003246-200007000-00018</doi><tpages>7</tpages></addata></record> |
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| source | MEDLINE; Journals@Ovid Ovid Autoload |
| subjects | Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy APACHE Biological and medical sciences Employment Female Health Status Health Surveys Hospital Mortality Humans Intensive care medicine Intensive Care Units Length of Stay Male Medical sciences Mental Health Middle Aged Miscellaneous Morbidity Patient Discharge Patient Satisfaction Prospective Studies Quality of Life Sex Distribution Surveys and Questionnaires Survival Rate |
| title | Survival, morbidity, and quality of life after discharge from intensive care |
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