Searching for the Autoimmune Thyroid Disease Susceptibility Genes: From Gene Mapping to Gene Function

The autoimmune thyroid diseases (AITD) are complex diseases that are caused by an interaction between susceptibility genes and environmental triggers. Genetic susceptibility, in combination with external factors (e.g., dietary iodine), is believed to initiate the autoimmune response to thyroid antig...

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Veröffentlicht in:	Endocrine reviews 2003-10, Vol.24 (5), p.694-717
Hauptverfasser:	Tomer, Yaron, Davies, Terry F
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Antigens, CD Antigens, Differentiation - genetics Autoimmune Diseases - genetics Biological and medical sciences Chromosome Mapping CTLA-4 Antigen Cytotoxicity Epidemiology Family Fundamental and applied biological sciences. Psychology Gene mapping Genes Genetic analysis Genetic Linkage Genetic Predisposition to Disease Genomic analysis Graves disease Histocompatibility antigen HLA HLA Antigens - genetics Humans Iodine Loci Lymphocytes Lymphocytes T Phenotypes Siblings Susceptibility Thyroglobulin Thyroid Thyroid diseases Thyroid Diseases - genetics Thyroid Diseases - immunology Thyroid gland Thyroid-stimulating hormone Thyroiditis Twin Studies as Topic Vertebrates: endocrinology
Online-Zugang:	Volltext
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