Characteristics and treatment outcomes of leprosy patients detected during a leprosy elimination campaign in Mozambique compared with routinely detected patients
The objective of this study is to assess whether the case-finding method is a determinant for diagnostic characteristics and treatment outcome of newly diagnosed leprosy patients in Northern Mozambique. This is a retrospective cohort study of 3202 patients on the differences between entrance charact...
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| Veröffentlicht in: | Leprosy review 2003-09, Vol.74 (3), p.229-239 |
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| creator | PHAFF, C VAN DEN BROEK, J MACARTHUR, A. JR NDEVE, A STUIP, Y |
| description | The objective of this study is to assess whether the case-finding method is a determinant for diagnostic characteristics and treatment outcome of newly diagnosed leprosy patients in Northern Mozambique. This is a retrospective cohort study of 3202 patients on the differences between entrance characteristics and treatment outcome in self-reporting patients and patients detected during a leprosy elimination campaign (LEC) in 1999 in Northern Mozambique. As a consequence of LEC activities, 3 times more patients were found compared with the same period 1 year earlier. After the LEC, case detection remained higher in the years 2000-2002 compared with the years preceding the LEC. More young ( |
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No gender imbalance was found in diagnosed LEC patients contrary to self-reporting patient groups. Comparing patients detected during a LEC in 1999 with the passive group of 1998 and 1999 showed a slight but statistically significant better treatment result for the passive group. The classification of leprosy (in favour of PB) and age (in favour of older age groups) were also determinants for favourable treatment outcomes. Volunteers had a significantly better result of treatment compared with trained nurses and regardless of detection method. LEC proved to be a useful addition to the National Leprosy and Tuberculosis Programme in Northern Mozambique. As a result, many new cases were diagnosed and put on treatment and their treatment results were very satisfactory. LEC had a lasting impact on case finding. Volunteers make a valuable contribution to leprosy control in Mozambique because they have consistently better treatment results compared with nurses.</description><identifier>ISSN: 0305-7518</identifier><identifier>EISSN: 2162-8807</identifier><identifier>PMID: 14577468</identifier><identifier>CODEN: LEREAA</identifier><language>eng</language><publisher>Colchester: LEPRA</publisher><subject>Adolescent ; Adult ; Bacterial diseases ; Biological and medical sciences ; Child ; Child, Preschool ; Cohort Studies ; Female ; Fundamental and applied biological sciences. Psychology ; General aspects ; Health Promotion ; Human bacterial diseases ; Humans ; Infant ; Infant, Newborn ; Infectious diseases ; Leprostatic Agents - therapeutic use ; Leprosy ; Leprosy - diagnosis ; Leprosy - drug therapy ; Leprosy - epidemiology ; Leprosy - etiology ; Leprosy - prevention & control ; Male ; Mass Screening - methods ; Medical sciences ; Microbiology ; Middle Aged ; Mozambique ; Outcome Assessment (Health Care) ; Retrospective Studies ; Treatment Outcome ; Tropical bacterial diseases</subject><ispartof>Leprosy review, 2003-09, Vol.74 (3), p.229-239</ispartof><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15434083$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14577468$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PHAFF, C</creatorcontrib><creatorcontrib>VAN DEN BROEK, J</creatorcontrib><creatorcontrib>MACARTHUR, A. JR</creatorcontrib><creatorcontrib>NDEVE, A</creatorcontrib><creatorcontrib>STUIP, Y</creatorcontrib><title>Characteristics and treatment outcomes of leprosy patients detected during a leprosy elimination campaign in Mozambique compared with routinely detected patients</title><title>Leprosy review</title><addtitle>Lepr Rev</addtitle><description>The objective of this study is to assess whether the case-finding method is a determinant for diagnostic characteristics and treatment outcome of newly diagnosed leprosy patients in Northern Mozambique. This is a retrospective cohort study of 3202 patients on the differences between entrance characteristics and treatment outcome in self-reporting patients and patients detected during a leprosy elimination campaign (LEC) in 1999 in Northern Mozambique. As a consequence of LEC activities, 3 times more patients were found compared with the same period 1 year earlier. After the LEC, case detection remained higher in the years 2000-2002 compared with the years preceding the LEC. More young (<15 years) paucibacillary (PB) cases were diagnosed during LEC activities with, surprisingly, equal percentage of disability grades. No gender imbalance was found in diagnosed LEC patients contrary to self-reporting patient groups. Comparing patients detected during a LEC in 1999 with the passive group of 1998 and 1999 showed a slight but statistically significant better treatment result for the passive group. The classification of leprosy (in favour of PB) and age (in favour of older age groups) were also determinants for favourable treatment outcomes. Volunteers had a significantly better result of treatment compared with trained nurses and regardless of detection method. LEC proved to be a useful addition to the National Leprosy and Tuberculosis Programme in Northern Mozambique. As a result, many new cases were diagnosed and put on treatment and their treatment results were very satisfactory. LEC had a lasting impact on case finding. Volunteers make a valuable contribution to leprosy control in Mozambique because they have consistently better treatment results compared with nurses.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Health Promotion</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infectious diseases</subject><subject>Leprostatic Agents - therapeutic use</subject><subject>Leprosy</subject><subject>Leprosy - diagnosis</subject><subject>Leprosy - drug therapy</subject><subject>Leprosy - epidemiology</subject><subject>Leprosy - etiology</subject><subject>Leprosy - prevention & control</subject><subject>Male</subject><subject>Mass Screening - methods</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Middle Aged</subject><subject>Mozambique</subject><subject>Outcome Assessment (Health Care)</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Tropical bacterial diseases</subject><issn>0305-7518</issn><issn>2162-8807</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkNtKAzEQhoMotlZfQXKjdws57elSiieoeKPXZXLYNrLJrkkWqW_jmxqwtVcDM9___zNzguaMVqxoGlKfojnhpCzqkjYzdBHjByGc0pafoxkVZV2Lqpmjn-UWAqhkgo3JqojBa5yCgeSMT3iYkhqciXjocG_GMMQdHiHZPItYm2SyUmM9Bes3GP4R01tnfeYGjxW4EezGY-vxy_ANTtrPyeBsO0LI4i-btjjkIOtNvzuaHmIu0VkHfTRX-7pA7w_3b8unYvX6-Ly8WxUj43UqWqWl5lIIIJII0lU158rwSjDa1p1qVAktJ9Ro2fGuZbkldceoYhUpJROcL9Dtn28-IS8Y09rZqEzfgzfDFNc1ZW1bkSqD13twks7o9Risg7BbH56agZs9AFFB3wXwysYjVwouSMP5L2SEhqQ</recordid><startdate>20030901</startdate><enddate>20030901</enddate><creator>PHAFF, C</creator><creator>VAN DEN BROEK, J</creator><creator>MACARTHUR, A. JR</creator><creator>NDEVE, A</creator><creator>STUIP, Y</creator><general>LEPRA</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20030901</creationdate><title>Characteristics and treatment outcomes of leprosy patients detected during a leprosy elimination campaign in Mozambique compared with routinely detected patients</title><author>PHAFF, C ; VAN DEN BROEK, J ; MACARTHUR, A. JR ; NDEVE, A ; STUIP, Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p237t-9cdbd3b44a0b040f6733ce3642197fc8c5a9301edbf3f927fcbdf21c2605b2433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Health Promotion</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infectious diseases</topic><topic>Leprostatic Agents - therapeutic use</topic><topic>Leprosy</topic><topic>Leprosy - diagnosis</topic><topic>Leprosy - drug therapy</topic><topic>Leprosy - epidemiology</topic><topic>Leprosy - etiology</topic><topic>Leprosy - prevention & control</topic><topic>Male</topic><topic>Mass Screening - methods</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Middle Aged</topic><topic>Mozambique</topic><topic>Outcome Assessment (Health Care)</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Tropical bacterial diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PHAFF, C</creatorcontrib><creatorcontrib>VAN DEN BROEK, J</creatorcontrib><creatorcontrib>MACARTHUR, A. JR</creatorcontrib><creatorcontrib>NDEVE, A</creatorcontrib><creatorcontrib>STUIP, Y</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Leprosy review</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PHAFF, C</au><au>VAN DEN BROEK, J</au><au>MACARTHUR, A. 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This is a retrospective cohort study of 3202 patients on the differences between entrance characteristics and treatment outcome in self-reporting patients and patients detected during a leprosy elimination campaign (LEC) in 1999 in Northern Mozambique. As a consequence of LEC activities, 3 times more patients were found compared with the same period 1 year earlier. After the LEC, case detection remained higher in the years 2000-2002 compared with the years preceding the LEC. More young (<15 years) paucibacillary (PB) cases were diagnosed during LEC activities with, surprisingly, equal percentage of disability grades. No gender imbalance was found in diagnosed LEC patients contrary to self-reporting patient groups. Comparing patients detected during a LEC in 1999 with the passive group of 1998 and 1999 showed a slight but statistically significant better treatment result for the passive group. The classification of leprosy (in favour of PB) and age (in favour of older age groups) were also determinants for favourable treatment outcomes. Volunteers had a significantly better result of treatment compared with trained nurses and regardless of detection method. LEC proved to be a useful addition to the National Leprosy and Tuberculosis Programme in Northern Mozambique. As a result, many new cases were diagnosed and put on treatment and their treatment results were very satisfactory. LEC had a lasting impact on case finding. Volunteers make a valuable contribution to leprosy control in Mozambique because they have consistently better treatment results compared with nurses.</abstract><cop>Colchester</cop><pub>LEPRA</pub><pmid>14577468</pmid><tpages>11</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Bacterial diseases Biological and medical sciences Child Child, Preschool Cohort Studies Female Fundamental and applied biological sciences. Psychology General aspects Health Promotion Human bacterial diseases Humans Infant Infant, Newborn Infectious diseases Leprostatic Agents - therapeutic use Leprosy Leprosy - diagnosis Leprosy - drug therapy Leprosy - epidemiology Leprosy - etiology Leprosy - prevention & control Male Mass Screening - methods Medical sciences Microbiology Middle Aged Mozambique Outcome Assessment (Health Care) Retrospective Studies Treatment Outcome Tropical bacterial diseases |
| title | Characteristics and treatment outcomes of leprosy patients detected during a leprosy elimination campaign in Mozambique compared with routinely detected patients |
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