Decreased function of Fas in patients displaying delayed progression of HIV-induced immune deficiency

In acquired immune deficiency syndrome patients, apoptosis of uninfected lymphocytes may contribute to development of immune deficiency. This process may involve recruitment of Fas by human immunodeficiency virus products. In line with this possibility, the viral envelope glycoprotein gp120 does not...

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Veröffentlicht in:	The hematology journal : the official journal of the European Haematology Association 2001, Vol.2 (4), p.220-227
Hauptverfasser:	Bottarel, F, Bonissoni, S, Lucia, M B, Bragardo, M, Bensi, T, Buonfiglio, D, Mezzatesta, C, DiFranco, D, Balotta, C, Capobianchi, M R, Dianzani, I, Cauda, R, Dianzani, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - diagnosis Acquired Immunodeficiency Syndrome - genetics Antibodies, Monoclonal Apoptosis - genetics Apoptosis - physiology Case-Control Studies Disease Progression Family Health fas Receptor - genetics fas Receptor - immunology fas Receptor - physiology HIV Long-Term Survivors Humans Prognosis Signal Transduction - genetics Signal Transduction - physiology T-Lymphocytes - metabolism T-Lymphocytes - physiology T-Lymphocytes - virology
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