Role of actin and myosin in the mechanism of the decrease of myocardial contractility and efficiency of energy transformation by myocardial myofibrils in chronic heart failure in humans

Experiments with hybrid myocardial fibers showed that abnormalities of actin (basic protein of fine sarcomer threads) are responsible for reduced contraction rate, decreased developed force, and low efficiency of cardiomyocyte contraction in chronic heart failure caused by dilatation and ischemic ca...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bulletin of experimental biology and medicine 2001-11, Vol.132 (5), p.1100-1105
Hauptverfasser:	Karsanov, N V, Guledani, N E, Kuchava, L T
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - physiology Adenosine Triphosphate - metabolism Aged Heart Failure Humans Hydrogen-Ion Concentration Hydrolysis Middle Aged Myocardial Contraction Myocardium - metabolism Myofibrils - metabolism Myosins - physiology Temperature Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!