Generation and role of angiostatin in human platelets

Platelets regulate new blood vessel growth, because they contain a number of angiogenesis promoters and inhibitors. Additionally, platelets contain matrix metalloproteinases (MMPs), which when released mediate platelet adhesion and aggregation, and plasminogen, a fibrinolytic system enzyme that serv...

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Veröffentlicht in:	Blood 2003-11, Vol.102 (9), p.3217-3223
Hauptverfasser:	Jurasz, Paul, Alonso, David, Castro-Blanco, Susana, Murad, Ferid, Radomski, Marek W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - biosynthesis Angiogenesis Inhibitors - isolation & purification Angiostatins - biosynthesis Angiostatins - isolation & purification Angiostatins - physiology Biological and medical sciences Blood coagulation. Blood cells Blood Platelets - metabolism Blood Platelets - physiology Blotting, Western Chromatography, Affinity Collagen Endothelium, Vascular - cytology Fundamental and applied biological sciences. Psychology Humans Molecular and cellular biology Neovascularization, Physiologic Platelet Platelet Aggregation - physiology Umbilical Veins - cytology
Online-Zugang:	Volltext
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