Hofmannolin, a cyanopeptolin from Scytonema hofmanni PCC 7110

Two depsipeptide metabolites, scyptolin A and B, were reported recently from the axenically grown terrestrial cyanobacterium Scytonema hofmanni PCC 7110. A related, novel depsipeptide was isolated from this Scytonema and designated hofmannolin. The amino acid analysis in context with infrared, mass...

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Veröffentlicht in:	Phytochemistry (Oxford) 2003-11, Vol.64 (6), p.1061-1067
Hauptverfasser:	Matern, Ute, Oberer, Lukas, Erhard, Marcel, Herdman, Michael, Weckesser, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology antibacterial properties antifungal properties Bacteriology Biological and medical sciences Candida albicans - drug effects chemical structure Cyanobacteria Cyanobacteria - chemistry Cyanobacteria - genetics cyanopeptolin Cyanopeptolins Cyanophyta Cyclic depsipeptides cyclic peptides depsipeptides elastase enzyme inhibition Fundamental and applied biological sciences. Psychology Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Hofmannolin isolation Microbiology Morphology, structure, chemical composition Nuclear Magnetic Resonance, Biomolecular papain peptidases Peptides, Cyclic - chemistry Peptides, Cyclic - isolation & purification Peptides, Cyclic - pharmacology plasmin Protease Inhibitors - isolation & purification Protease Inhibitors - pharmacology Protein Conformation Scytonema Scytonema hofmanni spectral analysis Spectrometry, Mass, Electrospray Ionization - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods thrombin trypsin
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