Addition of Bu3SnLi to tert-Butanesulfinimines as an Efficient Route to Chiral, Nonracemic α-Aminoorganostannanes

Addition of Bu3SnLi to tert-Butanesulfinimines as an Efficient Route to Chiral, Nonracemic α-Aminoorganostannanes

Addition of Bu3SnLi to tert-butanesulfinimines proceeds with high diastereoselectivities to provide the expected adducts in excellent yields and typically with dr = >99:1. These adducts are readily converted to enantiomerically enriched N-Boc-protected α-aminoorganostannanes with complete retenti...

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Veröffentlicht in:Organic letters 2003-10, Vol.5 (22), p.4215-4218
Hauptverfasser: Kells, Kevin W, Chong, J. Michael
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creator Kells, Kevin W
Chong, J. Michael
description Addition of Bu3SnLi to tert-butanesulfinimines proceeds with high diastereoselectivities to provide the expected adducts in excellent yields and typically with dr = >99:1. These adducts are readily converted to enantiomerically enriched N-Boc-protected α-aminoorganostannanes with complete retention of configuration.
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title Addition of Bu3SnLi to tert-Butanesulfinimines as an Efficient Route to Chiral, Nonracemic α-Aminoorganostannanes
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