Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

A number of environmental and industrial chemicals are reported to possess androgenic or antiandrogenic activities. These androgenic endocrine disrupting chemicals may disrupt the endocrine system of humans and wildlife by mimicking or antagonizing the functions of natural hormones. The present stud...

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Veröffentlicht in:	Chemical research in toxicology 2003-10, Vol.16 (10), p.1338-1358
Hauptverfasser:	Fang, Hong, Tong, Weida, Branham, William S, Moland, Carrie L, Dial, Stacy L, Hong, Huixiao, Xie, Qian, Perkins, Roger, Owens, William, Sheehan, Daniel M
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen Receptor Antagonists Androgens Animals Benzhydryl Compounds - chemistry Benzhydryl Compounds - metabolism Flutamide - chemistry Flutamide - metabolism Humans Hydrocarbons, Aromatic - chemistry Hydrocarbons, Aromatic - metabolism Hydrogen Bonding Hydrophobic and Hydrophilic Interactions Isoflavones - chemistry Isoflavones - metabolism Ligands Models, Molecular Phenol - chemistry Phenol - metabolism Phthalic Acids - chemistry Phthalic Acids - metabolism Phytoestrogens Plant Preparations - chemistry Plant Preparations - metabolism Polychlorinated Biphenyls - chemistry Polychlorinated Biphenyls - metabolism Protein Binding Rats Receptors, Androgen - metabolism Steroids - chemistry Steroids - metabolism Structure-Activity Relationship
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