IL-11 Selectively Inhibits Aeroallergen-Induced Pulmonary Eosinophilia and Th2 Cytokine Production

IL-11 is a pleiotropic cytokine that induces tissue remodeling with subepithelial fibrosis when expressed in the airway. Its effects on the Th2-dominated airway inflammation that is characteristic of asthma, however, are poorly understood. To characterize the effects of IL-11 on Th2 tissue inflammat...

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Veröffentlicht in:The Journal of immunology (1950) 2000-08, Vol.165 (4), p.2222-2231
Hauptverfasser: Wang, Jingming, Homer, Robert J, Hong, Lielie, Cohn, Lauren, Lee, Chun Guen, Jung, Sungsoo, Elias, Jack A
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Sprache:eng
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