Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation

This study assessed parameters of free radical damage to biomolecules, mitochondrial superoxide production, superoxide dismutase, and catalase activities and their relationship to sepsis mortality. Prospective animal study in a university laboratory for experimental. 140 male Wistar rats. The animal...

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Veröffentlicht in:	Intensive care medicine 2003-10, Vol.29 (10), p.1782-1789
Hauptverfasser:	RITTER, Cristiane, ANDRADES, Michael, DAL-PIZZOL, Felipe, FROTA, Mario Luis C, BONATTO, Fernanda, PINHO, Ricardo A, POLYDORO, Manuela, KLAMT, Fabio, PINHEIRO, Cleovaldo T. S, MENNA-BARRETO, Sérgio S, MOREIRA, José Claudio F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Bacterial diseases Bacterial sepsis Biological and medical sciences Cecal Diseases - complications Cecum Free radicals Human bacterial diseases Infectious diseases Intensive care Intestinal Perforation - complications Laparotomy Ligation Lipid peroxidation Male Medical sciences Mortality Oxidative Stress Prospective Studies Random Allocation Rats Rats, Wistar Sepsis Sepsis - etiology Sepsis - metabolism Sepsis - mortality Tumor necrosis factor-TNF
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