Low-density lipoprotein receptor gene mutation analysis and clinical correlation in Belgian hypercholesterolaemics

It is generally believed that patients with familial hypercholesterolaemia (FH) have a higher cardiovascular risk than hypercholesterolaemics without a defect in the low-density lipoprotein receptor (LDLR) gene. However, no conclusive evidence to support this view has yet been presented. We investig...

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Veröffentlicht in:	Molecular and cellular probes 2001-12, Vol.15 (6), p.329-336
Hauptverfasser:	Van Gaal, L.F., Peeters, A.V., De Block, C.E.M., de Leeuw, I.H., Thiart, R., Kotze, M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Belgium Child Coronary Disease - etiology Coronary Disease - genetics familial hypercholesterolaemia, LDL receptor gene, cardiovascular disease Female Humans Hypercholesterolemia - genetics Hyperlipoproteinemia Type II - genetics Male Middle Aged Mutation Receptors, LDL - genetics Regression Analysis Risk Factors
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