High-risk Corneal Allografts Are Capable of Stimulating Complement Dependent Cytolytic Antibodies

PURPOSE.To prospectively characterize serum antibody responses in high-risk corneal allografts. METHODS.Orthotopic and heterotopic C3H (H-2) corneas were transplanted to CB6F1 (H-2) recipient mice. Individual serum samples were collected at days 7, 14, 21, and 28 from orthotopically and heterotopica...

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Veröffentlicht in:	Cornea 2000-07, Vol.19 (4), p.521-525
Hauptverfasser:	Hargrave, Sylvia L, Taherzadeh, Sherine, Hegde, Sushma, Niederkorn, Jerry
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Complement Fixation Tests Complement System Proteins - immunology Corneal Transplantation - immunology Cytotoxicity, Immunologic - immunology Enzyme-Linked Immunosorbent Assay Female Graft Rejection - immunology Immunoglobulin G - immunology Isoantibodies - immunology Mice Mice, Inbred C3H Prospective Studies Th1 Cells - immunology Transplantation, Homologous
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