Shifting paradigms: biopharmaceuticals versus low molecular weight drugs

Biopharmaceuticals are pharmaceutical products consisting of (glyco)proteins. Nowadays a substantial part of the FDA-approved drugs belong to this class of drugs. Biopharmaceuticals deserve special attention as they have a number of characteristics that set them aside from low molecular weight drugs...

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Veröffentlicht in:	International journal of pharmaceutics 2003-11, Vol.266 (1), p.3-16
Hauptverfasser:	Crommelin, Daan J.A., Storm, Gert, Verrijk, Ruud, de Leede, Leo, Jiskoot, Wim, Hennink, Wim E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biogenerics Biological and medical sciences Biologicals Biopharmaceuticals Biopharmaceutics - methods General pharmacology Glycoproteins - chemical synthesis Glycoproteins - pharmacokinetics Glycoproteins - therapeutic use Humans Immunogenicity Medical sciences Nucleic Acids - chemical synthesis Nucleic Acids - pharmacokinetics Nucleic Acids - therapeutic use Pharmaceutical Preparations - chemical synthesis Pharmaceutical Preparations - metabolism Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments PK–PD
Online-Zugang:	Volltext
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