Serial MRI after transient focal cerebral ischemia in rats: dynamics of tissue injury, blood-brain barrier damage, and edema formation

With the advent of thrombolytic therapy for acute stroke, reperfusion-associated mechanisms of tissue injury have assumed greater importance. In this experimental study, we used several MRI techniques to monitor the dynamics of secondary ischemic damage, blood-brain barrier (BBB) disturbances, and t...

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Veröffentlicht in:	Stroke (1970) 2000-08, Vol.31 (8), p.1965-1973
Hauptverfasser:	Neumann-Haefelin, T, Kastrup, A, de Crespigny, A, Yenari, M A, Ringer, T, Sun, G H, Moseley, M E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basal Ganglia - blood supply Basal Ganglia - pathology Blood-Brain Barrier Brain Edema - diagnosis Brain Edema - etiology Brain Edema - metabolism Cerebrovascular Circulation Ischemic Attack, Transient - complications Ischemic Attack, Transient - diagnosis Ischemic Attack, Transient - metabolism Magnetic Resonance Imaging Male Rats Rats, Sprague-Dawley Recurrence Reperfusion Injury - complications Reperfusion Injury - diagnosis Reperfusion Injury - metabolism Temporal Lobe - blood supply Temporal Lobe - pathology
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