Human epithelial cancers secrete immunoglobulin G with unidentified specificity to promote growth and survival of tumor cells

Immunoglobulins (Igs) are found thus far only to be produced by differentiated B lymphocytes. By immunohistochemistry analysis, in situ hybridization, and laser capture microdissection-assisted single-cell PCR, we demonstrate that human cancers of epithelial origin, including carcinomas of breast, c...

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