Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy : pharmacological data from the Viradapt Study

In a prospective randomized study, the impact of plasma protease inhibitor (PI) trough levels on changes in HIV RNA were assessed in patients treated with genotypic-guided therapy. Patients failing combination therapy (HIV-1 RNA > 10,000 copies/ml, and at least 6 months of therapy with nucleoside...

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Veröffentlicht in:	AIDS (London) 2000-07, Vol.14 (10), p.1333-1339
Hauptverfasser:	DURANT, J, CLEVENBERGH, P, GARRAFFO, R, HALFON, P, ICARD, S, DEL GIUDICE, P, MONTAGNE, N, SCHAPIRO, J. M, DELLAMONICA, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Drug Resistance, Microbial - genetics Female Genotype HIV Infections - blood HIV Infections - drug therapy HIV Infections - virology HIV Protease Inhibitors - blood HIV Protease Inhibitors - therapeutic use HIV-1 - genetics Human immunodeficiency virus Human immunodeficiency virus 1 Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments proteinase inhibitor RNA, Viral - blood RNA, Viral - genetics Treatment Failure
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