Corticotropin-Releasing Hormone Type I Receptor Messenger Ribonucleic Acid and Protein Levels in the Ovine Fetal Pituitary: Ontogeny and Effect of Chronic Cortisol Administration

Abstract In sheep, the ACTH secretory response to CRH in vivo or in vitro changes as a function of development, with peak responses occurring several weeks before term (145 days of gestation). CRH-stimulated ACTH secretion is mediated via the G protein-coupled CRH type I (CRH R1) receptor. We used a...

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Veröffentlicht in:Endocrinology (Philadelphia) 2000-08, Vol.141 (8), p.2870-2876
Hauptverfasser: Green, Jennifer L., Figueroa, Jorge P., Massmann, G. Angela, Schwartz, Jeffrey, Rose, James C.
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Sprache:eng
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