Validation of the quality of life questionnaire in arterial hypertension (HQALY) for its use in Spain. Relationship between clinical variables and quality of life. Investigator Group of the HQALY study
To evaluate the measurement properties of the Hypertension Quality of Life (HQALY) questionnaire, under normal clinical practice conditions, and the relationship between quality of life and clinical variables in patients with hypertension. Observational, prospective and multi-centred study. 92 prima...
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description | To evaluate the measurement properties of the Hypertension Quality of Life (HQALY) questionnaire, under normal clinical practice conditions, and the relationship between quality of life and clinical variables in patients with hypertension.
Observational, prospective and multi-centred study.
92 primary care centres in Spain.
269 patients, of both sexes and over 17, with hypertension, stratified by age (18-44, 45-64 and over 64), sex and organic complaint. 106 individuals over 17 with normal tension were chosen at random.
Intensification of treatment in hypertense patients.
Administration of the HQALY and the EuroQol-5D at every attendance (patients, basal and at a month; controls, basal). In addition, at the basal attendance social-demographic and clinical features were recorded, and at the attendance at a month the clinical features and changes in health status.
Mean time of administration was 28 (23) minutes.
factor analysis showed two dimensions, state of mind and somatic manifestations, which correlated most closely with the dimensions of anxiety/depression (0.64) and pain/discomfort (0.55) on the EQ-5D, respectively. HQALY scores were higher (worse quality of life) in patients than in controls without hypertension (p < 0.01). Reliability: intraclass correlation coefficient was 0.88 in state of mind and 0.76 in somatic manifestations. Cronbach's alpha was 0.96 and 0.89, respectively. Sensitivity: the "size of the effect" at a month from starting treatment for hypertension was 0.40. Hypertension for over 10 years, more organs affected, gravity and morbid obesity were associated with worse quality of life, especially in the state-of-mind dimension. Cardiac frequency correlated closer with state of mind than somatic manifestations.
The HQALY is the first specific hypertension questionnaire developed in Spain which has been shown valid, reliable and sensitive to changes. However, the number of items on it must be reduced for routine use in clinical practice. |
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Observational, prospective and multi-centred study.
92 primary care centres in Spain.
269 patients, of both sexes and over 17, with hypertension, stratified by age (18-44, 45-64 and over 64), sex and organic complaint. 106 individuals over 17 with normal tension were chosen at random.
Intensification of treatment in hypertense patients.
Administration of the HQALY and the EuroQol-5D at every attendance (patients, basal and at a month; controls, basal). In addition, at the basal attendance social-demographic and clinical features were recorded, and at the attendance at a month the clinical features and changes in health status.
Mean time of administration was 28 (23) minutes.
factor analysis showed two dimensions, state of mind and somatic manifestations, which correlated most closely with the dimensions of anxiety/depression (0.64) and pain/discomfort (0.55) on the EQ-5D, respectively. HQALY scores were higher (worse quality of life) in patients than in controls without hypertension (p < 0.01). Reliability: intraclass correlation coefficient was 0.88 in state of mind and 0.76 in somatic manifestations. Cronbach's alpha was 0.96 and 0.89, respectively. Sensitivity: the "size of the effect" at a month from starting treatment for hypertension was 0.40. Hypertension for over 10 years, more organs affected, gravity and morbid obesity were associated with worse quality of life, especially in the state-of-mind dimension. Cardiac frequency correlated closer with state of mind than somatic manifestations.
The HQALY is the first specific hypertension questionnaire developed in Spain which has been shown valid, reliable and sensitive to changes. However, the number of items on it must be reduced for routine use in clinical practice.</description><identifier>ISSN: 0212-6567</identifier><identifier>PMID: 10927826</identifier><language>spa</language><publisher>Spain</publisher><subject>Adolescent ; Adult ; Aged ; Case-Control Studies ; Female ; Health Status ; Humans ; Hypertension - complications ; Hypertension - psychology ; Male ; Middle Aged ; Prospective Studies ; Quality of Life ; Quality-Adjusted Life Years ; Reproducibility of Results ; Sensitivity and Specificity ; Sex Factors ; Spain ; Surveys and Questionnaires</subject><ispartof>Atención primaria, 2000-06, Vol.26 (2), p.96-103</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10927826$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dalfó Baqué, A</creatorcontrib><creatorcontrib>Badia Llach, X</creatorcontrib><creatorcontrib>Roca-Cusachs Coll, A</creatorcontrib><creatorcontrib>Aristegui Ruiz, I</creatorcontrib><creatorcontrib>Roset Gamisans, M</creatorcontrib><title>Validation of the quality of life questionnaire in arterial hypertension (HQALY) for its use in Spain. Relationship between clinical variables and quality of life. Investigator Group of the HQALY study</title><title>Atención primaria</title><addtitle>Aten Primaria</addtitle><description>To evaluate the measurement properties of the Hypertension Quality of Life (HQALY) questionnaire, under normal clinical practice conditions, and the relationship between quality of life and clinical variables in patients with hypertension.
Observational, prospective and multi-centred study.
92 primary care centres in Spain.
269 patients, of both sexes and over 17, with hypertension, stratified by age (18-44, 45-64 and over 64), sex and organic complaint. 106 individuals over 17 with normal tension were chosen at random.
Intensification of treatment in hypertense patients.
Administration of the HQALY and the EuroQol-5D at every attendance (patients, basal and at a month; controls, basal). In addition, at the basal attendance social-demographic and clinical features were recorded, and at the attendance at a month the clinical features and changes in health status.
Mean time of administration was 28 (23) minutes.
factor analysis showed two dimensions, state of mind and somatic manifestations, which correlated most closely with the dimensions of anxiety/depression (0.64) and pain/discomfort (0.55) on the EQ-5D, respectively. HQALY scores were higher (worse quality of life) in patients than in controls without hypertension (p < 0.01). Reliability: intraclass correlation coefficient was 0.88 in state of mind and 0.76 in somatic manifestations. Cronbach's alpha was 0.96 and 0.89, respectively. Sensitivity: the "size of the effect" at a month from starting treatment for hypertension was 0.40. Hypertension for over 10 years, more organs affected, gravity and morbid obesity were associated with worse quality of life, especially in the state-of-mind dimension. Cardiac frequency correlated closer with state of mind than somatic manifestations.
The HQALY is the first specific hypertension questionnaire developed in Spain which has been shown valid, reliable and sensitive to changes. However, the number of items on it must be reduced for routine use in clinical practice.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Case-Control Studies</subject><subject>Female</subject><subject>Health Status</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Hypertension - psychology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Quality of Life</subject><subject>Quality-Adjusted Life Years</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Sex Factors</subject><subject>Spain</subject><subject>Surveys and Questionnaires</subject><issn>0212-6567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUEFOwzAQzAFES-ELyCcEh1SOk9jJsaqgrVQJARUSp8hx1tTIdYLtFOWJ_IqktBdOu7M7Mzvas2CMSURCmlI2Ci6d-8SYkDxmF8EowjlhGaHj4OeNa1Vxr2qDaon8FtBX2498N0Ct5IDBDXvDlQWkDOLWg1Vco23XQN8bN6jvls-z9fs9krVFyjvUugP5teHKTNEL6MMRt1UNKsF_AxgktDJK9EZ73vuVGhzipvofYIpWZj9E-OC-917Yum1OWQ83kfNt1V0F55JrB9fHOgk2jw-b-TJcPy1W89k6bNKEhrTMIQMKwLJY5AQnImdJDKmgFY0YJhVPGZWCiYhQIhKc0ywTUqalKCXNcBpPgts_28bWh88UO-UEaM0N1K0r2CDEOOmJN0diW-6gKhqrdtx2xen38S-xoILX</recordid><startdate>20000630</startdate><enddate>20000630</enddate><creator>Dalfó Baqué, A</creator><creator>Badia Llach, X</creator><creator>Roca-Cusachs Coll, A</creator><creator>Aristegui Ruiz, I</creator><creator>Roset Gamisans, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20000630</creationdate><title>Validation of the quality of life questionnaire in arterial hypertension (HQALY) for its use in Spain. Relationship between clinical variables and quality of life. Investigator Group of the HQALY study</title><author>Dalfó Baqué, A ; Badia Llach, X ; Roca-Cusachs Coll, A ; Aristegui Ruiz, I ; Roset Gamisans, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p546-6b9e8e6ee783c9204c9743e5c6d61702da576fc7c1262c409688cff5bcbf68053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2000</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Case-Control Studies</topic><topic>Female</topic><topic>Health Status</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Hypertension - psychology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Quality of Life</topic><topic>Quality-Adjusted Life Years</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Sex Factors</topic><topic>Spain</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dalfó Baqué, A</creatorcontrib><creatorcontrib>Badia Llach, X</creatorcontrib><creatorcontrib>Roca-Cusachs Coll, A</creatorcontrib><creatorcontrib>Aristegui Ruiz, I</creatorcontrib><creatorcontrib>Roset Gamisans, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Atención primaria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dalfó Baqué, A</au><au>Badia Llach, X</au><au>Roca-Cusachs Coll, A</au><au>Aristegui Ruiz, I</au><au>Roset Gamisans, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validation of the quality of life questionnaire in arterial hypertension (HQALY) for its use in Spain. Relationship between clinical variables and quality of life. Investigator Group of the HQALY study</atitle><jtitle>Atención primaria</jtitle><addtitle>Aten Primaria</addtitle><date>2000-06-30</date><risdate>2000</risdate><volume>26</volume><issue>2</issue><spage>96</spage><epage>103</epage><pages>96-103</pages><issn>0212-6567</issn><abstract>To evaluate the measurement properties of the Hypertension Quality of Life (HQALY) questionnaire, under normal clinical practice conditions, and the relationship between quality of life and clinical variables in patients with hypertension.
Observational, prospective and multi-centred study.
92 primary care centres in Spain.
269 patients, of both sexes and over 17, with hypertension, stratified by age (18-44, 45-64 and over 64), sex and organic complaint. 106 individuals over 17 with normal tension were chosen at random.
Intensification of treatment in hypertense patients.
Administration of the HQALY and the EuroQol-5D at every attendance (patients, basal and at a month; controls, basal). In addition, at the basal attendance social-demographic and clinical features were recorded, and at the attendance at a month the clinical features and changes in health status.
Mean time of administration was 28 (23) minutes.
factor analysis showed two dimensions, state of mind and somatic manifestations, which correlated most closely with the dimensions of anxiety/depression (0.64) and pain/discomfort (0.55) on the EQ-5D, respectively. HQALY scores were higher (worse quality of life) in patients than in controls without hypertension (p < 0.01). Reliability: intraclass correlation coefficient was 0.88 in state of mind and 0.76 in somatic manifestations. Cronbach's alpha was 0.96 and 0.89, respectively. Sensitivity: the "size of the effect" at a month from starting treatment for hypertension was 0.40. Hypertension for over 10 years, more organs affected, gravity and morbid obesity were associated with worse quality of life, especially in the state-of-mind dimension. Cardiac frequency correlated closer with state of mind than somatic manifestations.
The HQALY is the first specific hypertension questionnaire developed in Spain which has been shown valid, reliable and sensitive to changes. However, the number of items on it must be reduced for routine use in clinical practice.</abstract><cop>Spain</cop><pmid>10927826</pmid><tpages>8</tpages></addata></record> |
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subjects | Adolescent Adult Aged Case-Control Studies Female Health Status Humans Hypertension - complications Hypertension - psychology Male Middle Aged Prospective Studies Quality of Life Quality-Adjusted Life Years Reproducibility of Results Sensitivity and Specificity Sex Factors Spain Surveys and Questionnaires |
title | Validation of the quality of life questionnaire in arterial hypertension (HQALY) for its use in Spain. Relationship between clinical variables and quality of life. Investigator Group of the HQALY study |
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