The voltage-sensitive motor protein and the Ca2+-sensitive cytoskeleton in developing rat cochlear outer hair cells

Cochlear outer hair cells (OHCs) possess a unique fast voltage‐driven motility associated with a voltage‐sensitive motor protein embedded in the basolateral membrane. This mechanism is believed to underlie the cochlear amplification in mammals. OHCs also have a Ca2+/calmodulin‐dependent mechanical p...

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Veröffentlicht in:	The European journal of neuroscience 2001-12, Vol.14 (12), p.1947-1952
Hauptverfasser:	Beurg, Maryline, Bouleau, Yohan, Dulon, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Animals, Newborn Calcium Signaling - drug effects Calcium Signaling - physiology Cell Differentiation - physiology Cell Membrane - drug effects Cell Membrane - metabolism Cell Movement - drug effects Cell Movement - physiology cochlea Cytoskeleton - drug effects Cytoskeleton - metabolism Electric Stimulation electromotility Hair Cells, Auditory, Outer - cytology Hair Cells, Auditory, Outer - growth & development Hair Cells, Auditory, Outer - metabolism Hearing - physiology Ion Channels - drug effects Ion Channels - metabolism ionomycin Ionomycin - pharmacology Ionophores - pharmacology Membrane Potentials - drug effects Membrane Potentials - physiology Molecular Motor Proteins - drug effects Molecular Motor Proteins - metabolism motor protein Organ Culture Techniques prestin Rats Rats, Wistar Signal Transduction - drug effects Signal Transduction - physiology
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