The cancer-associated Sm-like oncogene: A novel target for the gene therapy of pancreatic cancer

Background: The prognosis for pancreatic cancer (PC) remains dismal, providing a clear need for the development of novel therapies. We have previously shown that the cancer-associated Sm-like (CaSm) oncogene is overexpressed in the great majority of pancreatic tumors and is required to maintain the...

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Veröffentlicht in:	Surgery 2000-08, Vol.128 (2), p.353-360
Hauptverfasser:	Kelley, Joseph R., Brown, Jason M., Frasier, Melissa M., Baron, Paul L., Schweinfest, Clifford W., Vournakis, John N., Watson, Dennis K., Cole, David J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Animals Biological and medical sciences Cell Adhesion Cell Division Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Regulation, Neoplastic Genetic Therapy Genetic Vectors Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Mice Mice, SCID Oncogenes Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Polymerase Chain Reaction RNA, Antisense Time Factors Tumor Cells, Cultured Tumors
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