Three-year prognosis of depression in the community-dwelling elderly
Depression is the most common mental disorder in the community-dwelling elderly. To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome. The subjects, diagnosed depressed at year 0 using the GMS-AGECAT packa...
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| Veröffentlicht in: | British journal of psychiatry 2000-05, Vol.176 (5), p.453-457 |
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| container_title | British journal of psychiatry |
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| creator | Denihan, Aisling Kirby, Michael Bruce, Irene Cunningham, Conal Coakley, Davis Lawlor, Brian A. |
| description | Depression is the most common mental disorder in the community-dwelling elderly.
To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome.
The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years later. A number of factors were investigated for an association with recovery from, or persistence of, depression.
At follow-up, 30.2% of the depressed subjects had died, 34.9% had persistent or relapsed case-level depression, 24.5% had other case- or sub-case-level mental illness and 10.4% had recovered completely. Physical ill-health, bereavement and positive family history of depression were associated with poor outcome, whereas treatment with antidepressant medication significantly improved prognosis.
Late-life depression in community-dwelling subjects is a chronic condition. However, the positive response to antidepressant medication suggests that it should be vigorously treated. |
| doi_str_mv | 10.1192/bjp.176.5.453 |
| format | Article |
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To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome.
The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years later. A number of factors were investigated for an association with recovery from, or persistence of, depression.
At follow-up, 30.2% of the depressed subjects had died, 34.9% had persistent or relapsed case-level depression, 24.5% had other case- or sub-case-level mental illness and 10.4% had recovered completely. Physical ill-health, bereavement and positive family history of depression were associated with poor outcome, whereas treatment with antidepressant medication significantly improved prognosis.
Late-life depression in community-dwelling subjects is a chronic condition. However, the positive response to antidepressant medication suggests that it should be vigorously treated.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.176.5.453</identifier><identifier>PMID: 10912221</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Aged ; Anti-Anxiety Agents - therapeutic use ; Antidepressants ; Antidepressive Agents - therapeutic use ; Anxiety ; Benzodiazepines ; Bereavement ; Chronic Disease ; Chronic illnesses ; Cohort Studies ; Community ; Comorbidity ; Depressive Disorder - drug therapy ; Depressive Disorder - epidemiology ; Drugs ; Female ; Gender ; Geriatrics ; Health status ; Humans ; Interviews ; Ireland - epidemiology ; Logistic Models ; Male ; Medical prognosis ; Mental depression ; Mental disorders ; Multivariate Analysis ; Older people ; Prevalence ; Prognosis ; Psychiatry ; Psychosis ; Recurrence ; Risk Factors ; Social networks ; Treatment Outcome</subject><ispartof>British journal of psychiatry, 2000-05, Vol.176 (5), p.453-457</ispartof><rights>Copyright © 2000 The Royal College of Psychiatrists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-481f1b9ef0c5c4abd23673fef0a343edae624b1a7a28ac7926d89f114710ad373</citedby><cites>FETCH-LOGICAL-c422t-481f1b9ef0c5c4abd23673fef0a343edae624b1a7a28ac7926d89f114710ad373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007125000226627/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,780,784,12846,27924,27925,30999,55628</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10912221$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Denihan, Aisling</creatorcontrib><creatorcontrib>Kirby, Michael</creatorcontrib><creatorcontrib>Bruce, Irene</creatorcontrib><creatorcontrib>Cunningham, Conal</creatorcontrib><creatorcontrib>Coakley, Davis</creatorcontrib><creatorcontrib>Lawlor, Brian A.</creatorcontrib><title>Three-year prognosis of depression in the community-dwelling elderly</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>Depression is the most common mental disorder in the community-dwelling elderly.
To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome.
The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years later. A number of factors were investigated for an association with recovery from, or persistence of, depression.
At follow-up, 30.2% of the depressed subjects had died, 34.9% had persistent or relapsed case-level depression, 24.5% had other case- or sub-case-level mental illness and 10.4% had recovered completely. Physical ill-health, bereavement and positive family history of depression were associated with poor outcome, whereas treatment with antidepressant medication significantly improved prognosis.
Late-life depression in community-dwelling subjects is a chronic condition. However, the positive response to antidepressant medication suggests that it should be vigorously treated.</description><subject>Aged</subject><subject>Anti-Anxiety Agents - therapeutic use</subject><subject>Antidepressants</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Anxiety</subject><subject>Benzodiazepines</subject><subject>Bereavement</subject><subject>Chronic Disease</subject><subject>Chronic illnesses</subject><subject>Cohort Studies</subject><subject>Community</subject><subject>Comorbidity</subject><subject>Depressive Disorder - drug therapy</subject><subject>Depressive Disorder - epidemiology</subject><subject>Drugs</subject><subject>Female</subject><subject>Gender</subject><subject>Geriatrics</subject><subject>Health status</subject><subject>Humans</subject><subject>Interviews</subject><subject>Ireland - epidemiology</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Multivariate Analysis</subject><subject>Older people</subject><subject>Prevalence</subject><subject>Prognosis</subject><subject>Psychiatry</subject><subject>Psychosis</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Social networks</subject><subject>Treatment Outcome</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkEtLw0AURgdRtFaXbiUiuEs7r2SSpdQnFNzU9TCZuWmm5OVMQ8m_d6QFH7i6XDh897sHoSuCZ4TkdF5s-hkR6SyZ8YQdoQnhgsaEp8kxmmCMRUxogs_QufebsDJOxSk6IzgnlFIyQQ-rygHEIygX9a5bt523PurKyEDvwHvbtZFto20Fke6aZmjtdozNDuratusIagOuHi_QSalqD5eHOUXvT4-rxUu8fHt-XdwvY80p3cY8IyUpciixTjRXhaEsFawMu2KcgVGQUl4QJRTNlBY5TU2WlyR8RLAyTLAputvnhqYfA_itbKzXoYtqoRu8FOHXPE14AG__gJtucG3oJinLciayPNiaonhPadd576CUvbONcqMkWH7JlUGuDHJlIgMe-OtD6lA0YH7Qe5sBuNkDlV1XO-tAOt37UVe_QuaHo6opnDVr-O72_9lPX_yPrw</recordid><startdate>20000501</startdate><enddate>20000501</enddate><creator>Denihan, Aisling</creator><creator>Kirby, Michael</creator><creator>Bruce, Irene</creator><creator>Cunningham, Conal</creator><creator>Coakley, Davis</creator><creator>Lawlor, Brian A.</creator><general>Cambridge University Press</general><general>RCP</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7XB</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20000501</creationdate><title>Three-year prognosis of depression in the community-dwelling elderly</title><author>Denihan, Aisling ; Kirby, Michael ; Bruce, Irene ; Cunningham, Conal ; Coakley, Davis ; Lawlor, Brian A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-481f1b9ef0c5c4abd23673fef0a343edae624b1a7a28ac7926d89f114710ad373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Anti-Anxiety Agents - therapeutic use</topic><topic>Antidepressants</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Anxiety</topic><topic>Benzodiazepines</topic><topic>Bereavement</topic><topic>Chronic Disease</topic><topic>Chronic illnesses</topic><topic>Cohort Studies</topic><topic>Community</topic><topic>Comorbidity</topic><topic>Depressive Disorder - drug therapy</topic><topic>Depressive Disorder - epidemiology</topic><topic>Drugs</topic><topic>Female</topic><topic>Gender</topic><topic>Geriatrics</topic><topic>Health status</topic><topic>Humans</topic><topic>Interviews</topic><topic>Ireland - epidemiology</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Multivariate Analysis</topic><topic>Older people</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Psychiatry</topic><topic>Psychosis</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Social networks</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Denihan, Aisling</creatorcontrib><creatorcontrib>Kirby, Michael</creatorcontrib><creatorcontrib>Bruce, Irene</creatorcontrib><creatorcontrib>Cunningham, Conal</creatorcontrib><creatorcontrib>Coakley, Davis</creatorcontrib><creatorcontrib>Lawlor, Brian A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Sociology Collection</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Social Science Database</collection><collection>Sociology Database (ProQuest)</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Denihan, Aisling</au><au>Kirby, Michael</au><au>Bruce, Irene</au><au>Cunningham, Conal</au><au>Coakley, Davis</au><au>Lawlor, Brian A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Three-year prognosis of depression in the community-dwelling elderly</atitle><jtitle>British journal of psychiatry</jtitle><addtitle>Br J Psychiatry</addtitle><date>2000-05-01</date><risdate>2000</risdate><volume>176</volume><issue>5</issue><spage>453</spage><epage>457</epage><pages>453-457</pages><issn>0007-1250</issn><eissn>1472-1465</eissn><abstract>Depression is the most common mental disorder in the community-dwelling elderly.
To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome.
The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years later. A number of factors were investigated for an association with recovery from, or persistence of, depression.
At follow-up, 30.2% of the depressed subjects had died, 34.9% had persistent or relapsed case-level depression, 24.5% had other case- or sub-case-level mental illness and 10.4% had recovered completely. Physical ill-health, bereavement and positive family history of depression were associated with poor outcome, whereas treatment with antidepressant medication significantly improved prognosis.
Late-life depression in community-dwelling subjects is a chronic condition. However, the positive response to antidepressant medication suggests that it should be vigorously treated.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>10912221</pmid><doi>10.1192/bjp.176.5.453</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of psychiatry, 2000-05, Vol.176 (5), p.453-457 |
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| language | eng |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Cambridge University Press Journals Complete |
| subjects | Aged Anti-Anxiety Agents - therapeutic use Antidepressants Antidepressive Agents - therapeutic use Anxiety Benzodiazepines Bereavement Chronic Disease Chronic illnesses Cohort Studies Community Comorbidity Depressive Disorder - drug therapy Depressive Disorder - epidemiology Drugs Female Gender Geriatrics Health status Humans Interviews Ireland - epidemiology Logistic Models Male Medical prognosis Mental depression Mental disorders Multivariate Analysis Older people Prevalence Prognosis Psychiatry Psychosis Recurrence Risk Factors Social networks Treatment Outcome |
| title | Three-year prognosis of depression in the community-dwelling elderly |
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