Dysplasia of the submucous nerve plexus in slow-transit constipation of adults
AIM METHODS RESULTSThere were no major differences between patients and controls, except that patients had slightly thicker submucosal nerves than controls (30.8 ± 1.6 versus 25.5 ± 2.0 μm, P < 0.05) and more frequent heterotopic ganglion cells (32 versus 6%, P< 0.05). Neither discriminant ana...
Gespeichert in:
| Veröffentlicht in: | European journal of gastroenterology & hepatology 2000-07, Vol.12 (7), p.755-759 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 759 |
|---|---|
| container_issue | 7 |
| container_start_page | 755 |
| container_title | European journal of gastroenterology & hepatology |
| container_volume | 12 |
| creator | Voderholzer, Winfried A Wiebecke, Baldur Gerum, Markus Müller-Lissner, Stefan A |
| description | AIM
METHODS
RESULTSThere were no major differences between patients and controls, except that patients had slightly thicker submucosal nerves than controls (30.8 ± 1.6 versus 25.5 ± 2.0 μm, P < 0.05) and more frequent heterotopic ganglion cells (32 versus 6%, P< 0.05). Neither discriminant analysis of the morphometric data nor subjective evaluation was able to correctly classify the slides as originating from patients or controls.
CONCLUSIONSThe existence of the clinicopathological entity IND in adults with slow-transit constipation is unlikely. For further classification of slow-transit constipation, rectal biopsies do not appear to be useful at present. Eur J Gastroenterol Hepatol 12:755-759 |
| doi_str_mv | 10.1097/00042737-200012070-00007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71255524</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71255524</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3857-6690571c38608a8df9ab5965d6e76d5cd362804eaec700c3162aa194de8fd9f43</originalsourceid><addsrcrecordid>eNp1kU1P3DAQhi0EYhfKX6hyqLiF-iO24yPa0lJpVS6t1JvldSbaFG8SPA4L_x4vu7S9cJoZ6XlnrMeEFIxeMWr0Z0ppxbXQJc8d41TTMjdUH5E5q7Qopar1MZlTI6tSGfZ7Rs4Q_2RUC6ZPySwv4cZQPic_vjzjGBx2rhjaIq2hwGm1mfwwYdFDfIRiDPCUh64vMAzbMkXXY5cKP_SYutGlbuh3UddMIeEHctK6gHBxqOfk19ebn4vbcnn37fviell6UUtdKmWo1CwPitaublrjVtIo2SjQqpG-EYrXtAIHXlPqBVPcOWaqBuq2MW0lzsnlfu8Yh4cJMNlNhx5CcD3kp1vNuJSS78B6D_o4IEZo7Ri7jYvPllG7c2nfXNq_Lu2ryxz9eLiRjUDzX3AvLwOfDoBD70KbzfgO_3GVYLXYYdUe2w4hQcT7MG0h2jW4kNb2va8ULx-qi6g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71255524</pqid></control><display><type>article</type><title>Dysplasia of the submucous nerve plexus in slow-transit constipation of adults</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Voderholzer, Winfried A ; Wiebecke, Baldur ; Gerum, Markus ; Müller-Lissner, Stefan A</creator><creatorcontrib>Voderholzer, Winfried A ; Wiebecke, Baldur ; Gerum, Markus ; Müller-Lissner, Stefan A</creatorcontrib><description>AIM
METHODS
RESULTSThere were no major differences between patients and controls, except that patients had slightly thicker submucosal nerves than controls (30.8 ± 1.6 versus 25.5 ± 2.0 μm, P < 0.05) and more frequent heterotopic ganglion cells (32 versus 6%, P< 0.05). Neither discriminant analysis of the morphometric data nor subjective evaluation was able to correctly classify the slides as originating from patients or controls.
CONCLUSIONSThe existence of the clinicopathological entity IND in adults with slow-transit constipation is unlikely. For further classification of slow-transit constipation, rectal biopsies do not appear to be useful at present. Eur J Gastroenterol Hepatol 12:755-759</description><identifier>ISSN: 0954-691X</identifier><identifier>EISSN: 1473-5687</identifier><identifier>DOI: 10.1097/00042737-200012070-00007</identifier><identifier>PMID: 10929902</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Biopsy, Needle ; Chronic Disease ; Constipation - diagnosis ; Constipation - pathology ; Enteric Nervous System - pathology ; Enteric Nervous System - physiopathology ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastrointestinal Transit ; Humans ; Intestinal Mucosa - innervation ; Intestinal Mucosa - pathology ; Male ; Manometry ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Rectum - innervation ; Rectum - pathology ; Reference Values ; Sensitivity and Specificity ; Statistics, Nonparametric ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>European journal of gastroenterology & hepatology, 2000-07, Vol.12 (7), p.755-759</ispartof><rights>2000 Lippincott Williams & Wilkins, Inc.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3857-6690571c38608a8df9ab5965d6e76d5cd362804eaec700c3162aa194de8fd9f43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1431832$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10929902$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Voderholzer, Winfried A</creatorcontrib><creatorcontrib>Wiebecke, Baldur</creatorcontrib><creatorcontrib>Gerum, Markus</creatorcontrib><creatorcontrib>Müller-Lissner, Stefan A</creatorcontrib><title>Dysplasia of the submucous nerve plexus in slow-transit constipation of adults</title><title>European journal of gastroenterology & hepatology</title><addtitle>Eur J Gastroenterol Hepatol</addtitle><description>AIM
METHODS
RESULTSThere were no major differences between patients and controls, except that patients had slightly thicker submucosal nerves than controls (30.8 ± 1.6 versus 25.5 ± 2.0 μm, P < 0.05) and more frequent heterotopic ganglion cells (32 versus 6%, P< 0.05). Neither discriminant analysis of the morphometric data nor subjective evaluation was able to correctly classify the slides as originating from patients or controls.
CONCLUSIONSThe existence of the clinicopathological entity IND in adults with slow-transit constipation is unlikely. For further classification of slow-transit constipation, rectal biopsies do not appear to be useful at present. Eur J Gastroenterol Hepatol 12:755-759</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Chronic Disease</subject><subject>Constipation - diagnosis</subject><subject>Constipation - pathology</subject><subject>Enteric Nervous System - pathology</subject><subject>Enteric Nervous System - physiopathology</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastrointestinal Transit</subject><subject>Humans</subject><subject>Intestinal Mucosa - innervation</subject><subject>Intestinal Mucosa - pathology</subject><subject>Male</subject><subject>Manometry</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Rectum - innervation</subject><subject>Rectum - pathology</subject><subject>Reference Values</subject><subject>Sensitivity and Specificity</subject><subject>Statistics, Nonparametric</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0954-691X</issn><issn>1473-5687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1P3DAQhi0EYhfKX6hyqLiF-iO24yPa0lJpVS6t1JvldSbaFG8SPA4L_x4vu7S9cJoZ6XlnrMeEFIxeMWr0Z0ppxbXQJc8d41TTMjdUH5E5q7Qopar1MZlTI6tSGfZ7Rs4Q_2RUC6ZPySwv4cZQPic_vjzjGBx2rhjaIq2hwGm1mfwwYdFDfIRiDPCUh64vMAzbMkXXY5cKP_SYutGlbuh3UddMIeEHctK6gHBxqOfk19ebn4vbcnn37fviell6UUtdKmWo1CwPitaublrjVtIo2SjQqpG-EYrXtAIHXlPqBVPcOWaqBuq2MW0lzsnlfu8Yh4cJMNlNhx5CcD3kp1vNuJSS78B6D_o4IEZo7Ri7jYvPllG7c2nfXNq_Lu2ryxz9eLiRjUDzX3AvLwOfDoBD70KbzfgO_3GVYLXYYdUe2w4hQcT7MG0h2jW4kNb2va8ULx-qi6g</recordid><startdate>200007</startdate><enddate>200007</enddate><creator>Voderholzer, Winfried A</creator><creator>Wiebecke, Baldur</creator><creator>Gerum, Markus</creator><creator>Müller-Lissner, Stefan A</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200007</creationdate><title>Dysplasia of the submucous nerve plexus in slow-transit constipation of adults</title><author>Voderholzer, Winfried A ; Wiebecke, Baldur ; Gerum, Markus ; Müller-Lissner, Stefan A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3857-6690571c38608a8df9ab5965d6e76d5cd362804eaec700c3162aa194de8fd9f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Chronic Disease</topic><topic>Constipation - diagnosis</topic><topic>Constipation - pathology</topic><topic>Enteric Nervous System - pathology</topic><topic>Enteric Nervous System - physiopathology</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastrointestinal Transit</topic><topic>Humans</topic><topic>Intestinal Mucosa - innervation</topic><topic>Intestinal Mucosa - pathology</topic><topic>Male</topic><topic>Manometry</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Rectum - innervation</topic><topic>Rectum - pathology</topic><topic>Reference Values</topic><topic>Sensitivity and Specificity</topic><topic>Statistics, Nonparametric</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Voderholzer, Winfried A</creatorcontrib><creatorcontrib>Wiebecke, Baldur</creatorcontrib><creatorcontrib>Gerum, Markus</creatorcontrib><creatorcontrib>Müller-Lissner, Stefan A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of gastroenterology & hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Voderholzer, Winfried A</au><au>Wiebecke, Baldur</au><au>Gerum, Markus</au><au>Müller-Lissner, Stefan A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dysplasia of the submucous nerve plexus in slow-transit constipation of adults</atitle><jtitle>European journal of gastroenterology & hepatology</jtitle><addtitle>Eur J Gastroenterol Hepatol</addtitle><date>2000-07</date><risdate>2000</risdate><volume>12</volume><issue>7</issue><spage>755</spage><epage>759</epage><pages>755-759</pages><issn>0954-691X</issn><eissn>1473-5687</eissn><abstract>AIM
METHODS
RESULTSThere were no major differences between patients and controls, except that patients had slightly thicker submucosal nerves than controls (30.8 ± 1.6 versus 25.5 ± 2.0 μm, P < 0.05) and more frequent heterotopic ganglion cells (32 versus 6%, P< 0.05). Neither discriminant analysis of the morphometric data nor subjective evaluation was able to correctly classify the slides as originating from patients or controls.
CONCLUSIONSThe existence of the clinicopathological entity IND in adults with slow-transit constipation is unlikely. For further classification of slow-transit constipation, rectal biopsies do not appear to be useful at present. Eur J Gastroenterol Hepatol 12:755-759</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>10929902</pmid><doi>10.1097/00042737-200012070-00007</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-691X |
| ispartof | European journal of gastroenterology & hepatology, 2000-07, Vol.12 (7), p.755-759 |
| issn | 0954-691X 1473-5687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71255524 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Biopsy, Needle Chronic Disease Constipation - diagnosis Constipation - pathology Enteric Nervous System - pathology Enteric Nervous System - physiopathology Female Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Transit Humans Intestinal Mucosa - innervation Intestinal Mucosa - pathology Male Manometry Medical sciences Middle Aged Other diseases. Semiology Rectum - innervation Rectum - pathology Reference Values Sensitivity and Specificity Statistics, Nonparametric Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | Dysplasia of the submucous nerve plexus in slow-transit constipation of adults |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T13%3A57%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dysplasia%20of%20the%20submucous%20nerve%20plexus%20in%20slow-transit%20constipation%20of%20adults&rft.jtitle=European%20journal%20of%20gastroenterology%20&%20hepatology&rft.au=Voderholzer,%20Winfried%20A&rft.date=2000-07&rft.volume=12&rft.issue=7&rft.spage=755&rft.epage=759&rft.pages=755-759&rft.issn=0954-691X&rft.eissn=1473-5687&rft_id=info:doi/10.1097/00042737-200012070-00007&rft_dat=%3Cproquest_cross%3E71255524%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71255524&rft_id=info:pmid/10929902&rfr_iscdi=true |