Heme oxygenase activity causes transient hypersensitivity to oxidative ultraviolet a radiation that depends on release of iron from heme

Heme oxygenase (HO) breaks down heme to iron, biliverdin, and carbon monoxide, and activity of this enzyme increases in many tissues and cell types after exposure to oxidative stress. There is evidence that increased HO activity is involved in long-term protective mechanisms against oxidative stress...

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Veröffentlicht in:Free radical biology & medicine 2000-04, Vol.28 (8), p.1191-1196
Hauptverfasser: Kvam, Egil, Hejmadi, Vidya, Ryter, Stefan, Pourzand, Charareh, Tyrrell, Rex M
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Sprache:eng
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