Tumor necrosis factor-α is expressed in donor heart and predicts right ventricular failure after human heart transplantation

BACKGROUND-Myocardial failure is an important problem after heart transplantation. Right ventricular (RV) failure is most common, although its mechanisms remain poorly understood. Inflammatory cytokines play an important role in heart failure. We studied the expression of tumor necrosis factor (TNF)...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2000-07, Vol.102 (3), p.326-331
Hauptverfasser:	BIRKS, E. J, OWEN, V. J, BURTON, P. B. J, BISHOP, A. E, BANNER, N. R, KHAGHANI, A, POLAK, J. M, YACOUB, M. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Blotting, Western Cardiac Output, Low - etiology Cytokines - metabolism Female Heart Transplantation Humans Immunohistochemistry Male Medical sciences Middle Aged Myocardium - metabolism Postoperative Complications Prognosis RNA, Messenger - metabolism Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Tissue Donors Treatment Outcome Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism Ventricular Dysfunction, Right - etiology
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