Ion chromatographic determination of inositol in infant formulae and clinical products for enteral feeding
An ion chromatographic method is described for the determination of inositol in infant formula and products for enteral feeding. A two-step procedure for hydrolysis and extraction of total inositol has been developed, involving alkaline hydrolysis with 3 M potassium hydroxide and enzymatic dephospho...
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| Veröffentlicht in: | Journal of Chromatography A 2000-05, Vol.879 (2), p.129-135 |
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| container_title | Journal of Chromatography A |
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| creator | Tagliaferri, Enrico G Bonetti, Graziano Blake, Christopher J |
| description | An ion chromatographic method is described for the determination of inositol in infant formula and products for enteral feeding. A two-step procedure for hydrolysis and extraction of total inositol has been developed, involving alkaline hydrolysis with 3
M potassium hydroxide and enzymatic dephosphorylation. Substances having a long chromatographic retention time were removed with an ion-exchange resin. Inositol was separated on a high-resolution ion-exchange column and detected by pulsed amperometric detection. Phytic acid interferes only slightly in the analysis. This method can be used for determination of total inositol in infant formulae, and enteral feeding products. The analytical method gave an average recovery of 94% from infant formula samples spiked with inositol and a recovery of 86±3% from products spiked with lecithin. |
| doi_str_mv | 10.1016/S0021-9673(00)00323-X |
| format | Article |
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M potassium hydroxide and enzymatic dephosphorylation. Substances having a long chromatographic retention time were removed with an ion-exchange resin. Inositol was separated on a high-resolution ion-exchange column and detected by pulsed amperometric detection. Phytic acid interferes only slightly in the analysis. This method can be used for determination of total inositol in infant formulae, and enteral feeding products. The analytical method gave an average recovery of 94% from infant formula samples spiked with inositol and a recovery of 86±3% from products spiked with lecithin.</description><identifier>ISSN: 0021-9673</identifier><identifier>DOI: 10.1016/S0021-9673(00)00323-X</identifier><identifier>PMID: 10893029</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Chromatography, Ion Exchange - methods ; Electrochemistry ; Enteral Nutrition ; Humans ; Infant ; Infant Food - analysis ; Inositol ; Inositol - analysis ; Lecithin ; Reproducibility of Results</subject><ispartof>Journal of Chromatography A, 2000-05, Vol.879 (2), p.129-135</ispartof><rights>2000 Elsevier Science B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-8fe0f31a2a8d849453af9b4cf76e21b4a3d17a454e72882f8d92c96ca43ea3c23</citedby><cites>FETCH-LOGICAL-c361t-8fe0f31a2a8d849453af9b4cf76e21b4a3d17a454e72882f8d92c96ca43ea3c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S002196730000323X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10893029$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tagliaferri, Enrico G</creatorcontrib><creatorcontrib>Bonetti, Graziano</creatorcontrib><creatorcontrib>Blake, Christopher J</creatorcontrib><title>Ion chromatographic determination of inositol in infant formulae and clinical products for enteral feeding</title><title>Journal of Chromatography A</title><addtitle>J Chromatogr A</addtitle><description>An ion chromatographic method is described for the determination of inositol in infant formula and products for enteral feeding. A two-step procedure for hydrolysis and extraction of total inositol has been developed, involving alkaline hydrolysis with 3
M potassium hydroxide and enzymatic dephosphorylation. Substances having a long chromatographic retention time were removed with an ion-exchange resin. Inositol was separated on a high-resolution ion-exchange column and detected by pulsed amperometric detection. Phytic acid interferes only slightly in the analysis. This method can be used for determination of total inositol in infant formulae, and enteral feeding products. The analytical method gave an average recovery of 94% from infant formula samples spiked with inositol and a recovery of 86±3% from products spiked with lecithin.</description><subject>Chromatography, Ion Exchange - methods</subject><subject>Electrochemistry</subject><subject>Enteral Nutrition</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant Food - analysis</subject><subject>Inositol</subject><subject>Inositol - analysis</subject><subject>Lecithin</subject><subject>Reproducibility of Results</subject><issn>0021-9673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1rHDEMhn1ISbZpf0LCnEJzmES2Z-fjVEpo2oVADkkhN6O15Y3DjL21PYX--3izS-ktIJCQXn09jJ1xuOLA2-sHAMHroe3kF4BLAClk_XTEFv_SJ-xjSi8AvINOHLMTDv0gQQwL9rIKvtLPMUyYwybi9tnpylCmODmP2ZVqsJXzIbkcxhIUs-hzZUOc5hGpQm8qPTrvNI7VNgYz65x25Yp8GVOSlsg4v_nEPlgcE30--FP26_b7483P-u7-x-rm212tZctz3VsCKzkK7E3fDM1Soh3WjbZdS4KvG5SGd9gsG-pE3wvbm0HoodXYSEKphTxlF_u55ZjfM6WsJpc0jSN6CnNSHRdL6KErwuVeqGNIKZJV2-gmjH8VB7UDq97Aqh1BBaDewKqn0nd-WDCvJzL_de2pFsHXvYDKm38cRZW0I68Lhkg6KxPcOyteAdTCjF4</recordid><startdate>20000526</startdate><enddate>20000526</enddate><creator>Tagliaferri, Enrico G</creator><creator>Bonetti, Graziano</creator><creator>Blake, Christopher J</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000526</creationdate><title>Ion chromatographic determination of inositol in infant formulae and clinical products for enteral feeding</title><author>Tagliaferri, Enrico G ; Bonetti, Graziano ; Blake, Christopher J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-8fe0f31a2a8d849453af9b4cf76e21b4a3d17a454e72882f8d92c96ca43ea3c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Chromatography, Ion Exchange - methods</topic><topic>Electrochemistry</topic><topic>Enteral Nutrition</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant Food - analysis</topic><topic>Inositol</topic><topic>Inositol - analysis</topic><topic>Lecithin</topic><topic>Reproducibility of Results</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tagliaferri, Enrico G</creatorcontrib><creatorcontrib>Bonetti, Graziano</creatorcontrib><creatorcontrib>Blake, Christopher J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Chromatography A</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tagliaferri, Enrico G</au><au>Bonetti, Graziano</au><au>Blake, Christopher J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ion chromatographic determination of inositol in infant formulae and clinical products for enteral feeding</atitle><jtitle>Journal of Chromatography A</jtitle><addtitle>J Chromatogr A</addtitle><date>2000-05-26</date><risdate>2000</risdate><volume>879</volume><issue>2</issue><spage>129</spage><epage>135</epage><pages>129-135</pages><issn>0021-9673</issn><abstract>An ion chromatographic method is described for the determination of inositol in infant formula and products for enteral feeding. A two-step procedure for hydrolysis and extraction of total inositol has been developed, involving alkaline hydrolysis with 3
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| subjects | Chromatography, Ion Exchange - methods Electrochemistry Enteral Nutrition Humans Infant Infant Food - analysis Inositol Inositol - analysis Lecithin Reproducibility of Results |
| title | Ion chromatographic determination of inositol in infant formulae and clinical products for enteral feeding |
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