Histone MacroH2A1.2 Is Concentrated in the XY-Body by the Early Pachytene Stage of Spermatogenesis

The pairing of sex chromosomes during meiosis in male mammals is associated with ongoing heterochromatinization and X inactivation. This process occurs in a specific area of the nucleus that can be discerned morphologically: the sex vesicle or XY-body. In contrast to X inactivation in the somatic ce...

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Veröffentlicht in:	Experimental cell research 2000-08, Vol.258 (2), p.254-260
Hauptverfasser:	Hoyer-Fender, Sigrid, Costanzi, Carl, Pehrson, John R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - metabolism Dosage Compensation, Genetic histone macroH2A Histones - genetics Histones - immunology Histones - physiology Immunohistochemistry Male male germ cells Meiosis - physiology Mice Mice, Inbred C57BL Nucleosomes - physiology Nucleosomes - ultrastructure Rabbits Rats sex vesicle Spermatogenesis - physiology Spermatozoa - physiology Spermatozoa - ultrastructure X Chromosome X inactivation Y Chromosome
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