$A Double-blind, Placebo-Controlled Study of Risperidone Addition in Serotonin Reuptake Inhibitor–Refractory Obsessive-compulsive Disorder$

A Double-blind, Placebo-Controlled Study of Risperidone Addition in Serotonin Reuptake Inhibitor–Refractory Obsessive-compulsive Disorder

BACKGROUND To date, only 1 controlled study has found a drug (haloperidol) to be efficacious in augmenting response in patients with obsessive-compulsive disorder (OCD) refractory to serotonin reuptake inhibitor (SRI) monotherapy; patients with comorbid chronic tic disorders showed a preferential re...

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Veröffentlicht in:	Archives of general psychiatry 2000-08, Vol.57 (8), p.794-801
Hauptverfasser:	McDougle, Christopher J, Epperson, C. Neill, Pelton, Gregory H, Wasylink, Suzanne, Price, Lawrence H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - administration & dosage Antipsychotic Agents - therapeutic use Biological and medical sciences Comorbidity Dopamine Antagonists - therapeutic use Double-Blind Method Drug Administration Schedule Drug Therapy, Combination Female Humans Male Medical sciences Middle Aged Neuropharmacology Obsessive-Compulsive Disorder - drug therapy Obsessive-Compulsive Disorder - epidemiology Obsessive-Compulsive Disorder - psychology Pharmacology. Drug treatments Placebos Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Risperidone - administration & dosage Risperidone - therapeutic use Schizotypal Personality Disorder - drug therapy Schizotypal Personality Disorder - epidemiology Serotonin Antagonists - therapeutic use Serotonin Uptake Inhibitors - therapeutic use Tics - drug therapy Tics - epidemiology Treatment Outcome
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