Feedback Inhibition of Sodium/Calcium Exchange by Mitochondrial Calcium Accumulation

Chinese hamster ovary cells expressing the bovine cardiac Na+/Ca2+ exchanger were subjected to two periods of 5 and 3 min, respectively, during which the extracellular Na+ concentration ([Na+]o) was reduced to 20 mm; these intervals were separated by a 5-min recovery period at 140 mm Na+o. The cytos...

Ausführliche Beschreibung