Effect of Angiotensin II Antagonist Eprosartan on Hyperglycemia-Induced Activation of Intrarenal Renin-Angiotensin System in Healthy Humans

We have previously reported that hyperglycemia in healthy human subjects increased the renal vasodilator response to the angiotensin-converting enzyme inhibitor captopril. This observation raised intriguing possibilities relevant to the pathogenesis of nephropathy in patients with diabetes mellitus....

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2000-07, Vol.36 (1), p.122-126
Hauptverfasser:	Osei, Suzette Y, Price, Deborah A, Laffel, Lori M. B, Lansang, Maria C, Hollenberg, Norman K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylates - pharmacology Adult Angiotensin II - antagonists & inhibitors Angiotensin II - blood Associated diseases and complications Biological and medical sciences Diabetes. Impaired glucose tolerance Diabetic Nephropathies - etiology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Glomerular Filtration Rate - drug effects Hemodynamics - drug effects Humans Hyperglycemia - physiopathology Imidazoles - pharmacology Kidney - drug effects Kidney - physiopathology Male Medical sciences Middle Aged Renal Circulation - drug effects Renin - blood Renin-Angiotensin System - drug effects Space life sciences Thiophenes
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