Basilar Artery Remodelling In The Genetically Hypertensive Rat: Effects Of Nitric Oxide Synthase Inhibition And Treatment With Valsartan And Enalapril

SUMMARY 1. The structure of the basilar artery and the relationship of structure to blood pressure and ventricular hypertrophy was examined in genetically hypertensive (GH) rats, their control normotensive (N) Wistar strain, GH given the nitric oxide synthase (NOS) inhibitor, NG‐nitro‐ L‐arginine me...

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Veröffentlicht in:	Clinical and Experimental Pharmacology and Physiology 2000-08, Vol.27 (8), p.642-646
Hauptverfasser:	Ledingham, JM, Laverty, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensin Receptor Antagonists Animals Antihypertensive Agents - therapeutic use basilar artery Basilar Artery - drug effects Basilar Artery - pathology blood pressure Blood Pressure - drug effects Brain - pathology enalapril Enalapril - therapeutic use Enzyme Inhibitors - therapeutic use genetic hypertension genetically hypertensive rats Hypertension - drug therapy Hypertension - genetics Hypertension - pathology Muscle, Smooth, Vascular - pathology NG-Nitroarginine Methyl Ester - therapeutic use Nitric Oxide Synthase - antagonists & inhibitors nitric oxide synthase inhibition Nitric Oxide Synthase Type III Rats Rats, Inbred SHR Stroke - pathology Tetrazoles - therapeutic use Valine - analogs & derivatives Valine - therapeutic use Valsartan Ventricular Function, Left - drug effects ventricular hypertrophy
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