Association and linkage studies of CRH and PENK genes in bipolar disorder: A collaborative IGSLI study

Corticotropin‐releasing hormone (CRH) and proenkephalin (PENK) are hypothalamic peptides involved in the stress response and hypothalamic‐pituitary axis regulation. Previous research has implicated these peptides in the pathogenesis of affective disorders. In this study we investigated two polymorph...

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Veröffentlicht in:	American journal of medical genetics 2000-04, Vol.96 (2), p.178-181
Hauptverfasser:	Alda, Martin, Turecki, Gustavo, Grof, Paul, Cavazzoni, Patrizia, Duffy, Anne, Grof, Eva, Ahrens, Bernd, Berghöfer, Anne, Müller-Oerlinghausen, Bruno, Dvořáková, Marta, Libigerová, Eva, Vojtĕchovský, Miloš, Zvolský, Petr, Joober, Ridha, Nilsson, Agneta, Prochazka, Helena, Licht, Rasmus W., Rasmussen, Niels A., Schou, Mogens, Vestergaard, Per, Holzinger, Anita, Schumann, Claudia, Thau, Kenneth, Rouleau, Guy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Biological and medical sciences bipolar disorder Bipolar Disorder - drug therapy Bipolar Disorder - etiology Bipolar Disorder - genetics Bipolar disorders Corticotropin-Releasing Hormone - genetics CRH Enkephalins - genetics Female Gene Frequency Genetic Linkage - genetics genetics Genotype Humans Linkage Disequilibrium - genetics linkage study lithium Lithium - therapeutic use Male Medical genetics Medical sciences Mental and behavioral disorders Middle Aged Mood disorders PENK Phenotype Protein Precursors - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry
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