Epidemiology and pathogenesis of Neisseria meningitidis
Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease...
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Veröffentlicht in: | Microbes and Infection 2000-05, Vol.2 (6), p.687-700 |
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description | Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease and led to progress in the development of the next generation of meningococcal vaccines. This review summarizes current knowledge of the human susceptibility to and the epidemiology and molecular pathogenesis of meningococcal disease. |
doi_str_mv | 10.1016/S1286-4579(00)00356-7 |
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Psychology</subject><subject>Humans</subject><subject>meningitis</subject><subject>Meningitis, Meningococcal - epidemiology</subject><subject>Meningitis, Meningococcal - microbiology</subject><subject>Meningococcal Infections - epidemiology</subject><subject>Meningococcal Infections - microbiology</subject><subject>Microbiology</subject><subject>Neisseria meningitidis</subject><subject>Neisseria meningitidis - pathogenicity</subject><subject>pathogenesis</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies</subject><subject>Virulence</subject><subject>virulence factors</subject><issn>1286-4579</issn><issn>1769-714X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0UtLw0AQB_BFFFurH0HJQUQP0dnsKzmJlPqAogcVvC2b3UldyaNmU6Hf3vSFR08zhx_DzPwJOaVwTYHKm1eapDLmQmWXAFcATMhY7ZEhVTKLFeUf-32_IwNyFMIXABVK8kMyoJCmXCYwJGoy9w4r35TNbBmZ2kVz0302M6wx-BA1RfSMPgRsvYkqrH098513PhyTg8KUAU-2dUTe7ydv48d4-vLwNL6bxpYp0cUZKiOtyZ2gjLmC8yQVAiSnhXIKcjBMmtSy1CXccHRZzlDmxticg8gkZmxELjZz523zvcDQ6coHi2VpamwWQSuacEho8i-kSmRZj3t4toWLvEKn562vTLvUu5_04HwLTLCmLFpTWx_-nEg4TVeb3W4Y9uf_eGx1sB5ri863aDvtGt_P1Kuw9DosvUpCA-h1WFqxXwgohMo</recordid><startdate>20000501</startdate><enddate>20000501</enddate><creator>Tzeng, Yih-Ling</creator><creator>Stephens, David S.</creator><general>Elsevier SAS</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>20000501</creationdate><title>Epidemiology and pathogenesis of Neisseria meningitidis</title><author>Tzeng, Yih-Ling ; Stephens, David S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-9e7a6cabd5133df4428550641f7d70b0a36a8c38d24a4ed9b3e6baacb40596e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Disease Susceptibility</topic><topic>epidemiology</topic><topic>Fundamental and applied biological sciences. 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subjects | Adult Bacteriology Biological and medical sciences Child Disease Susceptibility epidemiology Fundamental and applied biological sciences. Psychology Humans meningitis Meningitis, Meningococcal - epidemiology Meningitis, Meningococcal - microbiology Meningococcal Infections - epidemiology Meningococcal Infections - microbiology Microbiology Neisseria meningitidis Neisseria meningitidis - pathogenicity pathogenesis Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Virulence virulence factors |
title | Epidemiology and pathogenesis of Neisseria meningitidis |
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