Epidemiology and pathogenesis of Neisseria meningitidis

Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease...

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Veröffentlicht in:Microbes and Infection 2000-05, Vol.2 (6), p.687-700
Hauptverfasser: Tzeng, Yih-Ling, Stephens, David S.
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Stephens, David S.
description Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease and led to progress in the development of the next generation of meningococcal vaccines. This review summarizes current knowledge of the human susceptibility to and the epidemiology and molecular pathogenesis of meningococcal disease.
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adult
Bacteriology
Biological and medical sciences
Child
Disease Susceptibility
epidemiology
Fundamental and applied biological sciences. Psychology
Humans
meningitis
Meningitis, Meningococcal - epidemiology
Meningitis, Meningococcal - microbiology
Meningococcal Infections - epidemiology
Meningococcal Infections - microbiology
Microbiology
Neisseria meningitidis
Neisseria meningitidis - pathogenicity
pathogenesis
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Virulence
virulence factors
title Epidemiology and pathogenesis of Neisseria meningitidis
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