Gastrin releasing peptide-preferring bombesin receptors mediate growth of human renal cell carcinoma

Bombesin-like peptides typically act as neurotransmitters along the brain-gut axis and as growth factors in various human tissues. The present study demonstrates the expression of gastrin releasing peptide (GRP)-preferring bombesin receptors in human renal cell carcinoma but not in normal kidney tis...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2000-08, Vol.11 (8), p.1409-1418
Hauptverfasser:	PANSKY, A, DE WEERTH, A, FASLER-KAN, E, BOULAY, J.-L, SCHULZ, M, KETTERER, S, SELCK, C, BEGLINGER, C, VON SCHRENCK, T, HILDEBRAND, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animals Biological and medical sciences Bombesin - agonists Bombesin - antagonists & inhibitors Bombesin - metabolism Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Cell Division - physiology COS Cells Female Gastrin-Releasing Peptide - metabolism Humans Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Kidneys Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Receptors, Bombesin - genetics Receptors, Bombesin - metabolism Receptors, Bombesin - physiology RNA, Messenger - metabolism Tumor Cells, Cultured Tumors of the urinary system
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