Long-term effect of angiotensin-converting enzyme inhibitor in volume overloaded heart during growth: a controlled pilot study

OBJECTIVES This study examined whether long-term therapy with an angiotensin-converting enzyme (ACE) inhibitor reduces excessive increases in left ventricular (LV) mass as well as volume in growing children with aortic regurgitation or mitral regurgitation. BACKGROUND The ACE inhibitor reduces volum...

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Veröffentlicht in:	Journal of the American College of Cardiology 2000-07, Vol.36 (1), p.270-275
Hauptverfasser:	Mori, Yoshiki, Nakazawa, Makoto, Tomimatsu, Hirohumi, Momma, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Angiotensin-Converting Enzyme Inhibitors - therapeutic use Aortic Valve Insufficiency - complications Aortic Valve Insufficiency - drug therapy Aortic Valve Insufficiency - physiopathology Biological and medical sciences Cardiovascular system Child Child, Preschool Cilazapril - therapeutic use Disease Progression Echocardiography Enalapril - therapeutic use Follow-Up Studies Heart Ventricles - diagnostic imaging Heart Ventricles - drug effects Heart Ventricles - physiopathology Humans Hypertrophy, Left Ventricular - diagnostic imaging Hypertrophy, Left Ventricular - etiology Hypertrophy, Left Ventricular - prevention & control Infant Medical sciences Miscellaneous Mitral Valve Insufficiency - complications Mitral Valve Insufficiency - drug therapy Mitral Valve Insufficiency - physiopathology Myocardial Contraction - drug effects Observer Variation Pharmacology. Drug treatments Pilot Projects Treatment Outcome Ventricular Function, Left - drug effects Ventricular Function, Left - physiology
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