Metanephrogenic mesenchyme-to-epithelium transition induces profound expression changes of ion channels

The expression patterns of plasma membrane transporters that specify the epithelial cell type are acquired with ontogeny. To study this process during metanephrogenic mesenchyme-to-epithelium transition, branching ureteric buds with their adjacent mesenchymal blastema (mouse embryonic day E14) were...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2000-07, Vol.279 (1), p.F65-F76
Hauptverfasser:	Huber, S M, Braun, G S, Segerer, S, Veh, R W, Horster, M F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin Cadherins - genetics Cadherins - metabolism Cell Aggregation Cell Differentiation Cell Membrane - metabolism Cells, Cultured Cytoskeletal Proteins - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Electric Conductivity Epithelial Cells - cytology Epithelial Cells - metabolism Gene Expression Regulation, Developmental Immunohistochemistry Ion Channels - genetics Ion Channels - metabolism KCNQ Potassium Channels KCNQ1 Potassium Channel Kidney - cytology Kidney - embryology Kidney - metabolism Mesoderm - cytology Mesoderm - metabolism Mice PAX2 Transcription Factor Potassium - metabolism Potassium Channels - genetics Potassium Channels - metabolism Potassium Channels, Inwardly Rectifying Potassium Channels, Voltage-Gated RNA, Messenger - genetics RNA, Messenger - metabolism Sodium Chloride - metabolism Trans-Activators Transcription Factors - genetics Transcription Factors - metabolism WT1 Proteins
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