Regulation of the human fas promoter by YB-1, Puralpha and AP-1 transcription factors

Fas (CD95/Apo-1) gene expression is dysregulated in a number of diseased states. Towards understanding the regulation of fas gene expression, we previously identified activator and repressor elements within the human fas promoter. Using a combination of expression screening and reporter gene assays,...

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Veröffentlicht in:	Gene 2000-07, Vol.252 (1-2), p.1-13
Hauptverfasser:	Lasham, A, Lindridge, E, Rudert, F, Onrust, R, Watson, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins Cyclic AMP Response Element-Binding Protein - metabolism DNA, Complementary - genetics DNA, Complementary - isolation & purification DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism fas Receptor - genetics Gene Expression Regulation HeLa Cells Humans Jurkat Cells NFI Transcription Factors Nuclear Proteins Oligonucleotides - metabolism Promoter Regions, Genetic - genetics Protein Binding Regulatory Sequences, Nucleic Acid Transcription Factor AP-1 - metabolism Transcription Factors - metabolism Transcription, Genetic Tumor Cells, Cultured Y-Box-Binding Protein 1
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