$Role of redox‐active iron ions in the decomposition of S‐nitrosocysteine in subcellular fractions of porcine aorta$

Role of redox‐active iron ions in the decomposition of S‐nitrosocysteine in subcellular fractions of porcine aorta

We recently reported that degradation of S‐nitrosocysteine in homogenates of porcine aorta increased severalfold in the presence of Mg2+ ions [Kostka, P., Xu, B. & Skiles, E.H. (1999) J. Cardiovasc. Pharmacol.33, 665–670]. The objective of the present study was to examine this in greater detail....

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Veröffentlicht in:	European journal of biochemistry 2000-07, Vol.267 (14), p.4593-4599
Hauptverfasser:	Sorenson, Elizabeth, Skiles, Emily H., Xu, Bin, Aleryani, Samir, Kostka, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - metabolism Chelating Agents - pharmacology Cysteine - analogs & derivatives Cysteine - metabolism Cysteine - pharmacology Cytosol - metabolism Deferoxamine - pharmacology Dose-Response Relationship, Drug Ions Iron - metabolism Iron Chelating Agents - pharmacology iron ions Kinetics L-Lactate Dehydrogenase - metabolism Magnesium - metabolism Models, Chemical Muscle, Smooth, Vascular - metabolism nitroso compounds Nitroso Compounds - metabolism Pentetic Acid - pharmacology Phenanthrolines - pharmacology Pyridines - pharmacology S-Nitrosothiols Swine Time Factors vascular smooth muscle
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