Uptake and incorporation of docosahexaenoic acid (DHA) into neuronal cell body and neurite/nerve growth cone lipids : Evidence of compartmental DHA metabolism in nerve growth factor-differentiated PC12 cells

Docosahexaenoic acid (DHA) accumulates in nerve endings of the brain during development. It is released from the membrane during ischemia and electroconvulsive shock. DHA optimizes neurologic development, it is neuroprotective, and rat adrenopheochromocytoma (PC12) cells have decreased PLA2 activity...

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Veröffentlicht in:	Neurochemical research 2000-05, Vol.25 (5), p.715-723
Hauptverfasser:	MARTIN, R. E, WICKHAM, J. Q, OM, A.-S, SANDERS, J, CEBALLOS, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms Animals Biological and medical sciences Biological Transport Cell Differentiation - drug effects docosahexaenoic acid Docosahexaenoic Acids - metabolism Fundamental and applied biological sciences. Psychology Glycerol - metabolism Growth Cones - metabolism Growth Cones - ultrastructure Isolated neuron and nerve. Neuroglia Kinetics Nerve Growth Factor - pharmacology Neurites - metabolism Neurites - ultrastructure Neurons - cytology Neurons - metabolism PC12 Cells Pheochromocytoma Phosphatidylcholines - metabolism Phosphatidylethanolamines - metabolism Phospholipids - metabolism Rats Time Factors Tritium Vertebrates: nervous system and sense organs
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