Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft

Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal e...

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Veröffentlicht in:The Annals of thoracic surgery 2000-05, Vol.69 (5), p.1431-1438
Hauptverfasser: Royse, Alistair G, Royse, Colin F, Ajani, Andrew E, Symes, Emma, Maruff, Paul, Karagiannis, Steven, Gerraty, Richard P, Grigg, Leeanne E, Davis, Stephen M
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container_end_page 1438
container_issue 5
container_start_page 1431
container_title The Annals of thoracic surgery
container_volume 69
creator Royse, Alistair G
Royse, Colin F
Ajani, Andrew E
Symes, Emma
Maruff, Paul
Karagiannis, Steven
Gerraty, Richard P
Grigg, Leeanne E
Davis, Stephen M
description Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient. Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group. Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.
doi_str_mv 10.1016/S0003-4975(00)01173-5
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To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient. Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group. Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(00)01173-5</identifier><identifier>PMID: 10881818</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aortic Diseases - diagnostic imaging ; Arteriosclerosis - diagnostic imaging ; Biological and medical sciences ; Brain Damage, Chronic - prevention &amp; control ; Brain Diseases - prevention &amp; control ; Cardiopulmonary Bypass ; Coronary Artery Bypass - methods ; Coronary Disease - surgery ; Echocardiography, Transesophageal ; Female ; Humans ; Intracranial Embolism - diagnosis ; Male ; Medical sciences ; Middle Aged ; Neuropsychological Tests ; Postoperative Complications - prevention &amp; control ; Surgery (general aspects). 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To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient. Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group. Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</description><subject>Aortic Diseases - diagnostic imaging</subject><subject>Arteriosclerosis - diagnostic imaging</subject><subject>Biological and medical sciences</subject><subject>Brain Damage, Chronic - prevention &amp; control</subject><subject>Brain Diseases - prevention &amp; control</subject><subject>Cardiopulmonary Bypass</subject><subject>Coronary Artery Bypass - methods</subject><subject>Coronary Disease - surgery</subject><subject>Echocardiography, Transesophageal</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Embolism - diagnosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Postoperative Complications - prevention &amp; control</subject><subject>Surgery (general aspects). 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Transplantations, organ and tissue grafts. 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To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient. Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group. Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10881818</pmid><doi>10.1016/S0003-4975(00)01173-5</doi><tpages>8</tpages></addata></record>
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subjects Aortic Diseases - diagnostic imaging
Arteriosclerosis - diagnostic imaging
Biological and medical sciences
Brain Damage, Chronic - prevention & control
Brain Diseases - prevention & control
Cardiopulmonary Bypass
Coronary Artery Bypass - methods
Coronary Disease - surgery
Echocardiography, Transesophageal
Female
Humans
Intracranial Embolism - diagnosis
Male
Medical sciences
Middle Aged
Neuropsychological Tests
Postoperative Complications - prevention & control
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
title Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft
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