Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft
Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass. Methods. Aortic atheroma was detected using epiaortic and transesophageal e...
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Veröffentlicht in: | The Annals of thoracic surgery 2000-05, Vol.69 (5), p.1431-1438 |
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creator | Royse, Alistair G Royse, Colin F Ajani, Andrew E Symes, Emma Maruff, Paul Karagiannis, Steven Gerraty, Richard P Grigg, Leeanne E Davis, Stephen M |
description | Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass.
Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient.
Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group.
Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction. |
doi_str_mv | 10.1016/S0003-4975(00)01173-5 |
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Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient.
Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group.
Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(00)01173-5</identifier><identifier>PMID: 10881818</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aortic Diseases - diagnostic imaging ; Arteriosclerosis - diagnostic imaging ; Biological and medical sciences ; Brain Damage, Chronic - prevention & control ; Brain Diseases - prevention & control ; Cardiopulmonary Bypass ; Coronary Artery Bypass - methods ; Coronary Disease - surgery ; Echocardiography, Transesophageal ; Female ; Humans ; Intracranial Embolism - diagnosis ; Male ; Medical sciences ; Middle Aged ; Neuropsychological Tests ; Postoperative Complications - prevention & control ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart</subject><ispartof>The Annals of thoracic surgery, 2000-05, Vol.69 (5), p.1431-1438</ispartof><rights>2000 The Society of Thoracic Surgeons</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-76dbc3822bbd7d58135723d92a6528e172447b1a88f2a6766ec510abad5415453</citedby><cites>FETCH-LOGICAL-c455t-76dbc3822bbd7d58135723d92a6528e172447b1a88f2a6766ec510abad5415453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0003-4975(00)01173-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1386901$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10881818$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Royse, Alistair G</creatorcontrib><creatorcontrib>Royse, Colin F</creatorcontrib><creatorcontrib>Ajani, Andrew E</creatorcontrib><creatorcontrib>Symes, Emma</creatorcontrib><creatorcontrib>Maruff, Paul</creatorcontrib><creatorcontrib>Karagiannis, Steven</creatorcontrib><creatorcontrib>Gerraty, Richard P</creatorcontrib><creatorcontrib>Grigg, Leeanne E</creatorcontrib><creatorcontrib>Davis, Stephen M</creatorcontrib><title>Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass.
Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient.
Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group.
Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</description><subject>Aortic Diseases - diagnostic imaging</subject><subject>Arteriosclerosis - diagnostic imaging</subject><subject>Biological and medical sciences</subject><subject>Brain Damage, Chronic - prevention & control</subject><subject>Brain Diseases - prevention & control</subject><subject>Cardiopulmonary Bypass</subject><subject>Coronary Artery Bypass - methods</subject><subject>Coronary Disease - surgery</subject><subject>Echocardiography, Transesophageal</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Embolism - diagnosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Postoperative Complications - prevention & control</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLxDAQgIMouj5-gpKDiB6qeTRN9yQivkAQfBw8hTSZ7ka6TU1acf-9WXdRbzKHMJlvMuEbhPYpOaWEFmdPhBCe5WMpjgk5IZRKnok1NKJCsKxgYryORj_IFtqO8S2lLJU30RYlZUlTjJB-BDsYsLiFIfguzs3UN37ijG6wncd6aE3vfIuH6NoJhs5pH3pnMCTO6GCdnwTdTedYtxb3U8DwaZoEfwB-xalU97too9ZNhL3VuYNerq-eL2-z-4ebu8uL-8zkQvSZLGxleMlYVVlpRUm5kIzbMdOFYCVQyfJcVlSXZZ2uZFGAEZToSluRU5ELvoOOlu92wb8PEHs1c9FA0-gW_BCVpIwzxvMEiiVogo8xQK264GY6zBUlauFWfbtVC3GKEPXtVi0GHKwGDNUM7J-upcwEHK4AHZO_OujWuPjL8bIYE5qw8yUGycaHg6CicdCmJbgAplfWu39-8gVbnJaI</recordid><startdate>20000501</startdate><enddate>20000501</enddate><creator>Royse, Alistair G</creator><creator>Royse, Colin F</creator><creator>Ajani, Andrew E</creator><creator>Symes, Emma</creator><creator>Maruff, Paul</creator><creator>Karagiannis, Steven</creator><creator>Gerraty, Richard P</creator><creator>Grigg, Leeanne E</creator><creator>Davis, Stephen M</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000501</creationdate><title>Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft</title><author>Royse, Alistair G ; Royse, Colin F ; Ajani, Andrew E ; Symes, Emma ; Maruff, Paul ; Karagiannis, Steven ; Gerraty, Richard P ; Grigg, Leeanne E ; Davis, Stephen M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-76dbc3822bbd7d58135723d92a6528e172447b1a88f2a6766ec510abad5415453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aortic Diseases - diagnostic imaging</topic><topic>Arteriosclerosis - diagnostic imaging</topic><topic>Biological and medical sciences</topic><topic>Brain Damage, Chronic - prevention & control</topic><topic>Brain Diseases - prevention & control</topic><topic>Cardiopulmonary Bypass</topic><topic>Coronary Artery Bypass - methods</topic><topic>Coronary Disease - surgery</topic><topic>Echocardiography, Transesophageal</topic><topic>Female</topic><topic>Humans</topic><topic>Intracranial Embolism - diagnosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neuropsychological Tests</topic><topic>Postoperative Complications - prevention & control</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Royse, Alistair G</creatorcontrib><creatorcontrib>Royse, Colin F</creatorcontrib><creatorcontrib>Ajani, Andrew E</creatorcontrib><creatorcontrib>Symes, Emma</creatorcontrib><creatorcontrib>Maruff, Paul</creatorcontrib><creatorcontrib>Karagiannis, Steven</creatorcontrib><creatorcontrib>Gerraty, Richard P</creatorcontrib><creatorcontrib>Grigg, Leeanne E</creatorcontrib><creatorcontrib>Davis, Stephen M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Royse, Alistair G</au><au>Royse, Colin F</au><au>Ajani, Andrew E</au><au>Symes, Emma</au><au>Maruff, Paul</au><au>Karagiannis, Steven</au><au>Gerraty, Richard P</au><au>Grigg, Leeanne E</au><au>Davis, Stephen M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2000-05-01</date><risdate>2000</risdate><volume>69</volume><issue>5</issue><spage>1431</spage><epage>1438</epage><pages>1431-1438</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background. To examine the effect of screening the aorta for atheroma before aortic manipulation and use of exclusive Y graft revascularization on the incidence of neuropsychological dysfunction after coronary artery bypass.
Methods. Aortic atheroma was detected using epiaortic and transesophageal echocardiography. Atheroma avoidance was facilitated by use of the exclusive Y graft technique, which has no aortic coronary anastomoses. In the control group aortic atheroma was assessed by manual palpation, and we attempted to avoid any atheroma detected. In this group we also used aorta-coronary grafts. Transcranial Doppler imaging of the right middle cerebral artery was used to detect cerebral microemboli. Neuropsychological dysfunction was defined as a 20% or more decline in score for at least 20% of a neuropsychometric battery of ten tests for each patient.
Results. Late dysfunction at 57 ± 2 days postoperatively in the control group was 38.1% and in the echo/Y group was 3.8% (p′ = 0.012). Microemboli detected by transcranial Doppler imaging during periods of aortic manipulation was greater for those with late dysfunction (5.2 ± 3.0 compared with 0.5 ± 0.2) (p′ = 0.018). No clinical strokes occurred in either group.
Conclusions. The combined techniques of epiaortic screening and exclusive Y graft for coronary artery bypass operations resulted in a low incidence of late neuropsychological dysfunction.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10881818</pmid><doi>10.1016/S0003-4975(00)01173-5</doi><tpages>8</tpages></addata></record> |
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subjects | Aortic Diseases - diagnostic imaging Arteriosclerosis - diagnostic imaging Biological and medical sciences Brain Damage, Chronic - prevention & control Brain Diseases - prevention & control Cardiopulmonary Bypass Coronary Artery Bypass - methods Coronary Disease - surgery Echocardiography, Transesophageal Female Humans Intracranial Embolism - diagnosis Male Medical sciences Middle Aged Neuropsychological Tests Postoperative Complications - prevention & control Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart |
title | Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft |
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