Olfactory bulbectomy alters NMDA receptor levels in the rat prefrontal cortex

Olfactory bulbectomized (OBX) rats show a variety of behavioral and biochemical deficits that parallel human depression. We investigated the expression of glutamate receptor subtypes in cortical and subcortical brain regions following bilateral olfactory bulbectomy in adult rats. Quantitative recept...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 2000-08, Vol.37 (2), p.159-162
Hauptverfasser:	Webster, Harry H., Flores, Gonzalo, Marcotte, Eric R., Cecyre, Danielle, Quirion, Remi, Srivastava, Lalit K.
Format:	Artikel
Sprache:	eng
Schlagworte:	animal model Animals Autoradiography depression excitatory amino acids Male N-methyl-D-aspartate Olfactory Bulb - physiology olfactory bulbs Prefrontal Cortex - metabolism Rats Rats, Sprague-Dawley Receptors, AMPA - metabolism Receptors, Kainic Acid - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Time Factors
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