QSAR Model for Drug Human Oral Bioavailability

The quantitative structure−bioavailability relationship of 232 structurally diverse drugs was studied to evaluate the feasibility of constructing a predictive model for the human oral bioavailability of prospective new medicinal agents. The oral bioavailability determined in human adults was assigne...

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Veröffentlicht in:	Journal of medicinal chemistry 2000-06, Vol.43 (13), p.2575-2585
Hauptverfasser:	Yoshida, Fumitaka, Topliss, John G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Biological and medical sciences Biological Availability General pharmacology Humans Medical sciences Models, Biological Models, Molecular Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - classification Pharmacokinetics Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Structure-Activity Relationship
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